SCN8A monoclonal antibody (M04), clone 4G7 View larger

SCN8A monoclonal antibody (M04), clone 4G7

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Data sheet of SCN8A monoclonal antibody (M04), clone 4G7

BrandAbnova
Product typePrimary antibodies
ReactivityHuman
Host speciesMouse
ApplicationsIF,ELISA,WB-Re

More info about SCN8A monoclonal antibody (M04), clone 4G7

Brand: Abnova
Reference: H00006334-M04
Product name: SCN8A monoclonal antibody (M04), clone 4G7
Product description: Mouse monoclonal antibody raised against a partial recombinant SCN8A.
Clone: 4G7
Isotype: IgG2a Kappa
Gene id: 6334
Gene name: SCN8A
Gene alias: CerIII|MED|NaCh6|Nav1.6|PN4
Gene description: sodium channel, voltage gated, type VIII, alpha subunit
Genbank accession: NM_014191
Immunogen: SCN8A (NP_055006, 1854 a.a. ~ 1951 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Immunogen sequence/protein sequence: RVLGDSGELDILRQQMEERFVASNPSKVSYEPITTTLRRKQEEVSAVVLQRAYRGHLARRGFICKKTTSNKLENGGTHREKKESTPSTASLPSYDSVT
Protein accession: NP_055006
Storage buffer: In 1x PBS, pH 7.4
Storage instruction: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Quality control testing: Antibody Reactive Against Recombinant Protein.
Quality control testing picture: qc_test-H00006334-M04-1.jpg
Quality control testing picture note: Western Blot detection against Immunogen (36.52 KDa) .
Product type: Primary antibodies
Host species: Mouse
Antigen species / target species: Human
Reactivity: Human
Application image: H00006334-M04-4-8-1-L.jpg
Application image note: Immunofluorescence of monoclonal antibody to SCN8A on NIH/3T3 cell. [antibody concentration 10 ug/ml]
Applications: IF,ELISA,WB-Re
Shipping condition: Dry Ice
Publications: Na(v)1.1 localizes to axons of parvalbumin-positive inhibitory interneurons: a circuit basis for epileptic seizures in mice carrying an Scn1a gene mutation.Ogiwara I, Miyamoto H, Morita N, Atapour N, Mazaki E, Inoue I, Takeuchi T, Itohara S, Yanagawa Y, Obata K, Furuichi T, Hensch TK, Yamakawa K.
J Neurosci. 2007 May 30;27(22):5903-14.

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