Brand: | Abnova |
Reference: | H00005599-M11 |
Product name: | MAPK8 monoclonal antibody (M11), clone 2F11 |
Product description: | Mouse monoclonal antibody raised against a full length recombinant MAPK8. |
Clone: | 2F11 |
Isotype: | IgG2a Kappa |
Gene id: | 5599 |
Gene name: | MAPK8 |
Gene alias: | JNK|JNK1|JNK1A2|JNK21B1/2|PRKM8|SAPK1 |
Gene description: | mitogen-activated protein kinase 8 |
Genbank accession: | NM_002750.1 |
Immunogen: | MAPK8 (NP_002741.1, 1 a.a. ~ 384 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
Immunogen sequence/protein sequence: | MSRSKRDNNFYSVEIGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAILERNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNIIGLLNVFTPQKSLEEFQDVYIVMELMDANLCQVIQMELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSFMMTPYVVTRYYRAPEVILGMGYKENVDLWSVGCIMGEMVCHKILFPGRDYIDQWNKVIEQLGTPCPEFMKKLQPTVRTYVENRPKYAGYSFEKLFPDVLFPADSEHNKLKASQARDLLSKMLVIDASKRISVDEALQHPYINVWYDPSEAEAPPPKIPDKQLDEREHTIEEWKELIYKEVMDLEERTKNGVIRGQPSPLAQVQQ |
Protein accession: | NP_002741.1 |
Storage buffer: | In 1x PBS, pH 7.4 |
Storage instruction: | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
Quality control testing: | Antibody Reactive Against Recombinant Protein. |
Quality control testing picture: |  |
Quality control testing picture note: | Western Blot detection against Immunogen (67.87 KDa) . |
Product type: | Primary antibodies |
Host species: | Mouse |
Antigen species / target species: | Human |
Reactivity: | Human |
Application image: |  |
Application image note: | Western blot analysis of MAPK8 over-expressed 293 cell line, cotransfected with MAPK8 Validated Chimera RNAi ( Cat # H00005599-R01V ) (Lane 2) or non-transfected control (Lane 1). Blot probed with MAPK8 monoclonal antibody (M11) clone 2F11 (Cat # H00005599-M11 ). GAPDH ( 36.1 kDa ) used as specificity and loading control. |
Applications: | IF,S-ELISA,ELISA,WB-Re,WB-Tr,RNAi-Ab,PLA-Ce |
Shipping condition: | Dry Ice |
Publications: | Phosphorylation of Glutathione S-Transferase P1 (GSTP1) by Epidermal Growth Factor Receptor (EGFR) Promotes Formation of the GSTP1-c-Jun N-terminal kinase (JNK) Complex and Suppresses JNK Downstream Signaling and Apoptosis in Brain Tumor Cells.Okamura T, Antoun G, Keir ST, Friedman H, Bigner DD, Ali-Osman F. J Biol Chem. 2015 Dec 25;290(52):30866-78. doi: 10.1074/jbc.M115.656140. Epub 2015 Oct 1. |