HD monoclonal antibody (M05), clone 1H6 View larger

HD monoclonal antibody (M05), clone 1H6

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Data sheet of HD monoclonal antibody (M05), clone 1H6

BrandAbnova
Product typePrimary antibodies
ReactivityHuman
Host speciesMouse
ApplicationsS-ELISA,ELISA,WB-Re

More info about HD monoclonal antibody (M05), clone 1H6

Brand: Abnova
Reference: H00003064-M05
Product name: HD monoclonal antibody (M05), clone 1H6
Product description: Mouse monoclonal antibody raised against a partial recombinant HD.
Clone: 1H6
Isotype: IgG2a Kappa
Gene id: 3064
Gene name: HTT
Gene alias: HD|IT15
Gene description: huntingtin
Genbank accession: NM_002111
Immunogen: HD (NP_002102, 81 a.a. ~ 190 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Immunogen sequence/protein sequence: AVAEEPLHRPKKELSATKKDRVNHCLTICENIVAQSVRNSPEFQKLLGIAMELFLLCSDDAESDVRMVADECLNKVIKALMDSNLPRLQLELYKEIKKNGAPRSLRAALW
Protein accession: NP_002102
Storage buffer: In 1x PBS, pH 7.4
Storage instruction: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Quality control testing: Antibody Reactive Against Recombinant Protein.
Quality control testing picture: qc_test-H00003064-M05-1.jpg
Quality control testing picture note: Western Blot detection against Immunogen (37.84 KDa) .
Product type: Primary antibodies
Host species: Mouse
Antigen species / target species: Human
Reactivity: Human
Application image: H00003064-M05-9-20-1.jpg
Application image note: Detection limit for recombinant GST tagged HD is approximately 0.3ng/ml as a capture antibody.
Applications: S-ELISA,ELISA,WB-Re
Shipping condition: Dry Ice
Publications: IKK phosphorylates Huntingtin and targets it for degradation by the proteasome and lysosome.Thompson LM, Aiken CT, Kaltenbach LS, Agrawal N, Illes K, Khoshnan A, Martinez-Vincente M, Arrasate M, O'Rourke JG, Khashwji H, Lukacsovich T, Zhu YZ, Lau AL, Massey A, Hayden MR, Zeitlin SO, Finkbeiner S, Green KN, LaFerla FM, Bates G, Huang L, Patterson PH, Lo DC, Cuervo AM, Marsh JL, Steffan JS.
J Cell Biol. 2009 Dec 28;187(7):1083-99. Epub 2009 Dec 21.

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