Brand: | Abnova |
Reference: | H00002889-M01 |
Product name: | RAPGEF1 monoclonal antibody (M01), clone 3D10 |
Product description: | Mouse monoclonal antibody raised against a partial recombinant RAPGEF1. |
Clone: | 3D10 |
Isotype: | IgG2a Kappa |
Gene id: | 2889 |
Gene name: | RAPGEF1 |
Gene alias: | C3G|DKFZp781P1719|GRF2 |
Gene description: | Rap guanine nucleotide exchange factor (GEF) 1 |
Genbank accession: | BC041710 |
Immunogen: | RAPGEF1 (AAH41710, 1 a.a. ~ 110 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
Immunogen sequence/protein sequence: | MGNAIEKQKPLKRSHLYPWKQDSQRSHLSSFTMKLMDKFHSPKIKRTPSKKGKPAEVSVKIPEKPVNKEATDRFLPEGYPLPLDLEQQAVEFMSTSAVASRSQRQKNLSW |
Protein accession: | AAH41710 |
Storage buffer: | In 1x PBS, pH 7.4 |
Storage instruction: | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
Quality control testing: | Antibody Reactive Against Recombinant Protein. |
Quality control testing picture: |  |
Quality control testing picture note: | Western Blot detection against Immunogen (37.73 KDa) . |
Product type: | Primary antibodies |
Host species: | Mouse |
Antigen species / target species: | Human |
Reactivity: | Human |
Application image: |  |
Application image note: | Detection limit for recombinant GST tagged RAPGEF1 is approximately 0.1ng/ml as a capture antibody. |
Applications: | S-ELISA,ELISA,WB-Re,WB-Tr |
Shipping condition: | Dry Ice |
Publications: | The WAVE2 complex regulates T cell receptor signaling to integrins via Abl- and CrkL-C3G-mediated activation of Rap1.Nolz JC, Nacusi LP, Segovis CM, Medeiros RB, Mitchell JS, Shimizu Y, Billadeau DD. J Cell Biol. 2008 Sep 22;182(6):1231-44. |