PX-P4037-100
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Brand | ProteoGenix |
Product type | Proteins |
Origin species | Human |
Host species | Mammalian |
Proteogenix reference: | PX-P4037-100 |
Protein delivered with tag?: | Yes |
Product name: | Human Tumor necrosis factor receptor superfamily member 1A (TNFR1A) recombinant protein |
Description: | Receptor for TNFSF2/TNF-alpha and homotrimeric TNFSF1/lymphotoxin-alpha. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Contributes to the induction of non-cytocidal TNF effects including anti-viral state and activation of the acid sphingomyelinase. |
Fragment type: | Partial |
Expression system: | Eukaryotic expression |
Molecular weight with tag if any: | 24.35kDa |
Purity estimated: | 90% |
Uniprot id: | P19438 |
Uniprot link: | http://www.uniprot.org/uniprot/P19438 |
Aliases / synonyms: | CD120A, P55, TBP1, FPF, TNF-R, TNF-R-I, TNF-R55, TNFAR, TNFR1, TNFR55, TNFR60, P55-R, P60, Tumor necrosis factor receptor 1, Tumor necrosis factor-binding protein 1 |
Protein sequence (w/o tag): | MGLSTVPDLLLPLVLLELLVGIYPSGVIGLVPHLGDREKRDSVCPQGKYIHPQNNSICCTKCHKGTYLYNDCPGPGQDTDCRECESGSFTASENHLRHCLSCSKCRKEMGQVEISSCTVDRDTVCGCRKNQYRHYWSENLFQCFNCSLCLNGTVHLSCQEKQNTVCTCHAGFFLRENECVSCSNCKKSLECTKLCLPQIENVKGTEDSGTTGSHHHHHH |
Form: | Lyophilized |
Buffer: | 50 mM Tris-HCl pH 8, 150 mM NaCl |
Storage condition: | 4°C for short term (1 week), -20°C or -80°C for long term (avoid freezing/thawing cycles; addition of 20-40% glycerol improves cryoprotection) |
Delivery condition: | any condition |
Delivery lead time in business days: | 5-7 |