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Data sheet of Mouse Monoclonal antibody to human CSB (Cockayne syndrome B protein)
| Brand | ProteoGenix |
| Product type | Primary antibodies |
| Reactivity | Human |
| Clonality | Monoclonal |
| Host species | Mouse |
| Applications | E, WB, IP |
More info about Mouse Monoclonal antibody to human CSB (Cockayne syndrome B protein)
| Brand: | ProteoGenix |
| Proteogenix reference: | PTGX-CSB-3H8 |
| Product type: | Primary antibodies |
| Clonality: | Monoclonal |
| Product name: | Mouse Monoclonal antibody to human CSB (Cockayne syndrome B protein) |
| Host species: | Mouse |
| Target species: | Human |
| Reactivity: | Human |
| Applications: | E, WB, IP |
| Size: | 100µl |
| Clone name: | 1CSBâ€3H8 |
| Uniprot: | #N/A |
| Immunogen: | Synthetic peptide (RYRDDGDEDYYKQRLRRWNK) corresponding to aa 451-470 of human CSB. |
| Specificity: | human CSB. |
| Dilution: | 1/500-1/5000 |
| Alternative names: | 4732403I04 antibody, ARMD 5 antibody, ARMD5 antibody, ATP dependent helicase ERCC6 antibody, ATP-dependent helicase ERCC6 antibody, C130058G22Rik antibody, CKN 2 antibody, CKN2 antibody, Cockayne syndrome B protein antibody, Cockayne syndrome group B protein antibody, Cockayne syndrome protein CSB antibody, COFS antibody, COFS1 antibody, CS group B correcting antibody, CSB antibody, DNA excision repair protein ERCC 6 antibody, DNA excision repair protein ERCC-6 antibody, ERCC 6 antibody, ERCC6 antibody, ERCC6_HUMAN antibody, Excision repair cross complementing rodent repair deficiency, complementation group 6 antibody, OTTHUMP00000019581 antibody, RAD26 antibody, Rad26 homolog antibody, UVSS1 antibody |
| Isotype: | IgG1, k |
| Form: | liquid/frozen |
| Spec:conjugate/tag/label: | Unconjugated |
| Research area: | DNA Damage and Repair, Epigenetics & Nuclear Signalling, Neuroscience |
| Background information: | Mouse monoclonal anti-CSB (Cockayne syndrome B protein), clone 1CSB-3H8. Cockayne syndrome also named Neill-Dingwall syndrome is an infrequent automosal recessive neurodegenerative disease characterized by growth deficiency, impaired development of the nervous system, abnormal sensitivity to sunlight (photosensitivity), eye disorders and premature aging. Mutations in the ERCC8 (also known as CSA) gene or the ERCC6 (also known as CSB) gene are the origin of Cockayne syndrome. The proteins formed by these genes are implicated in repairing damaged DNA by the transcription-coupled repair mechanism, especially the DNA in active genes. |
| Publications: | 1. Bradsher J, Auriol J, Proietti de Santis L, Iben S, Vonesch JL, Grummt I, Egly JM. CSB is a component of RNA pol I transcription. Mol Cell. 2002 Oct;10(4):819-29. |
| Storage: | Store at -20°C. Aliquot to avoid repeated freezing and thawing. |
| Delivery lead time in business days in europe: | 2-3 |
| Delivery conditions: | Dry Ice |
| Related products: | - Mouse Monoclonal antibody to human Cyclin H - Mouse Monoclonal antibody to human Cyclin L1 - Mouse Monoclonal antibody to human DAXâ€1(NROB1) |