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Mouse Monoclonal antibody to human AID (Activation induced cytidine deaminase)
PTGX-AID-2E11
New product
Data sheet of Mouse Monoclonal antibody to human AID (Activation induced cytidine deaminase)
| Brand | ProteoGenix |
| Product type | Primary antibodies |
| Reactivity | Human, Mouse |
| Clonality | Monoclonal |
| Host species | Mouse |
| Applications | E, WB, IC,IP |
More info about Mouse Monoclonal antibody to human AID (Activation induced cytidine deaminase)
| Brand: | ProteoGenix |
| Proteogenix reference: | PTGX-AID-2E11 |
| Product type: | Primary antibodies |
| Clonality: | Monoclonal |
| Product name: | Mouse Monoclonal antibody to human AID (Activation induced cytidine deaminase) |
| Host species: | Mouse |
| Target species: | Human |
| Reactivity: | Human, Mouse |
| Applications: | E, WB, IC,IP |
| Size: | 100µl |
| Clone name: | 1AIDâ€2E11 |
| Uniprot: | #N/A |
| Immunogen: | Synthetic peptide coupled to Ovalbumin: (C)-EVDDLRDAFRMLGF corresponding to aa 185 to 198 of mouse AID. |
| Specificity: | mouse and human AID |
| Dilution: | 1/500 – 1/5000 |
| Alternative names: | Anti-AICDA antibody, Activation induced cytidine deaminase antibody, Activation induced deaminase antibody, Activation-induced cytidine deaminase antibody, AICDA antibody, AICDA_HUMAN antibody, AID antibody, ARP 2 antibody, ARP2 antibody, CDA 2 antibody, CDA2 antibody, Cytidine aminohydrolase antibody, HIGM2 antibody, Integrated into Burkitt's lymphoma cell line Ramos antibody |
| Isotype: | IgG1, k |
| Form: | liquid/frozen |
| Spec:conjugate/tag/label: | Unconjugated |
| Research area: | DNA Damage and Repair, Epigenetics & Nuclear Signalling, Immunology |
| Background information: | Mouse monoclonal anti-AID (Activation-induced cytidine deaminase), clone 1AID-2E11 recognizes mouse and human AID, encoded by the AICDA (Activation-induced cytidine deaminase) gene. AICDA was originally discovered as a homolog of the apolipoprotein B RNA-editing cytidine deaminase 1 (APOBEC1) that presented cytidine deaminase properties in stimulated B cell lines. AICDA is essential for somatic hypermutation and class switch recombination in B cells, but inappropriate or dysregulated expression AID is usually found in tumors and B cell neoplasms. This gene encodes a RNA-editing deaminase that is a member of the cytidine deaminase family. The protein is implicated in somatic hypermutation, gene conversion, and class-switch recombination of immunoglobulin genes. Deficiencies in this gene are the cause of autosomal recessive hyper-IgM immunodeficiency syndrome type 2 (HIGM2). |
| Publications: | / |
| Storage: | Store at -20°C. Aliquot to avoid repeated freezing and thawing. |
| Delivery lead time in business days in europe: | 2-3 |
| Delivery conditions: | Dry Ice |
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