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Drosophila TSH Recombinant Protein

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Data sheet of Drosophila TSH Recombinant Protein

BrandProteoGenix
Product typeProteins
Origin speciesFruit fry
Host speciesEscherichia coli (E. coli)

More info about Drosophila TSH Recombinant Protein

Brand: ProteoGenix
Proteogenix reference: PX-P1054-10
Protein delivered with tag?: No
Size: 10 ug
Product name: Drosophila TSH Recombinant Protein
Fragment type: Partial
Origin species: Fruit fry
Expression system: Prokaryotic expression
Host species: Escherichia coli (E. coli)
Molecular weight with tag if any: 19,65 kDa
Purity estimated: 0.8
Protein accession: AAA28983.1
Spec:entrez geneid: 35430
Spec:ncbi gene aliases: CG1374, ae, Tsh, T shirt, l(2)B4-2-12, l(2)04319, ae[l], Dmel\CG1374
Spec:swissprotid: P22265
Ncbi reference: AAA28983.1
Uniprot id: P22265
Uniprot link: http://www.uniprot.org/uniprot/P22265
Aliases / synonyms: TSH, teashirt, Protein teashirt, CG1374
Protein sequence (w/o tag): GPLGSANSSERCPSHDSNSSEHGGGAGSGGVGHRLDAAALSTGVMPGEGPTTLHSSFPAVPQSLPSQPPSMEAYLHMVAA AAQQYGFPLAAAAAAGAGPRLPLPLANEAAAPFKLPPQASPTASSNNSEALDFRTNLYGRAESAEPPASEGEEEEFDDGA NNPLDLSVGTRKRGHESEPQLGHIQVKKMFKSD
Form: liquid
Buffer: 3C-protease cleavage buffer: TrisHC 50mMl, NaCl 150mM, EDTA 1mM, DTT 1mM, pH7
Storage condition: 4°C for short term (1 week), -20°C or -80°C for long term (avoid freezing/thawing cycles; addition of 20-40% glycerol improves cryoprotection)
Delivery condition: Dry Ice
Delivery lead time in business days: 10-25
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Image: PX-P1054.jpg
Description: Protein teashirt from Drosophila melanogaster (Fruit fly) also known as TSH is initially localized in the cytoplasm soon after the blastoderm stage, and becomes nuclear by stage 9. It belongs to the teashirt C2H2-type zinc-finger protein family. It is a homeotic protein that acts downstream of Arm in the Wg cascade during embryogenesis to determine segment identity throughout the entire trunk. The protein shows a dynamic expression pattern during embryogenesis, expressed throughout embryonic, larval and adult development. TSH may play a role in wing hinge development. Possible involvement in chromatin structure for modulation of transcription. Binds DNA and can act as both a transcriptional repressor and activator.
Publications: 1: Fasano L, Röder L, Coré N, Alexandre E, Vola C, Jacq B, Kerridge S. The gene teashirt is required for the development of Drosophila embryonic trunk segments and encodes a protein with widely spaced zinc finger motifs. Cell. 1991 Jan 11;64(1):63-79. PubMed PMID: 1846092.

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