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Data sheet of Mouse Monoclonal to Nitrotyrosine
| Brand | Exbio |
| Product type | Primary antibodies |
| Reactivity | Broad |
| Clonality | Monoclonal |
More info about Mouse Monoclonal to Nitrotyrosine
| Brand: | Exbio |
| Product no.: | 11-693-C025 |
| Product type: | Primary antibodies |
| Host species: | Mouse |
| Product name: | Mouse Monoclonal to Nitrotyrosine |
| Antigen: | Nitrotyrosine |
| Clonality: | Monoclonal |
| Clone: | EM-30 |
| Isotype: | IgG1 |
| Immunogen: | NO2-Tyr-CH2-Thyroglobulin |
| Format: | purified |
| Specificity: | The antibody EM-30 detects nitrotyrosine group in biological material. It can be used as a marker for peroxynitrite formation in particular tissues. |
| Categories: | Epitope Tags, Miscellaneous (Human) |
| Concentration: | 1 mg/ml |
| Storage buffer: | Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4 |
| Storage / stability: | Store at 2-8°C. Do not freeze. Do not use after expiration date stamped on vial label. |
| Background: | Nitrotyrosine can be detected in proteins from a variety of tissues usually in association with pathological conditions. Reaction of nitric oxide with superoxide produces peroxynitrite, which can undergo heterolytic cleavage into nitronium and hydroxyl ions. Nitration of tyrosine residues by nitronium ion forms nitrotyrosine groups in the respective proteins. Nitrotyrosine is thus a marker for inflammation-associated tissue damage. |
| Purity: | > 95% (by SDS-PAGE) |
| Purification: | Purified by protein-A affinity chromatography |
| Related products: | - Mouse Monoclonal to NR2F6 - Mouse Monoclonal to NK1.1 / CD161bc (mouse) - Mouse Monoclonal to Notch 1 |
| Shipping condition: | Room temperature |