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Data sheet of Mouse Monoclonal to Myeloperoxidase (MPO)
| Brand | Exbio |
| Product type | Primary antibodies |
| Reactivity | Human |
| Clonality | Monoclonal |
More info about Mouse Monoclonal to Myeloperoxidase (MPO)
| Brand: | Exbio |
| Product no.: | 11-791-C025 |
| Product type: | Primary antibodies |
| Host species: | Mouse |
| Product name: | Mouse Monoclonal to Myeloperoxidase (MPO) |
| Antigen: | Myeloperoxidase (MPO) |
| Clonality: | Monoclonal |
| Clone: | MPO421-8B2 |
| Isotype: | IgG1 |
| Immunogen: | Human myeloperoxidase |
| Format: | purified |
| Specificity: | The mouse monoclonal antibody MPO421-8B2 recognizes human myeloperoxidase, a heme protein present in myeloblasts, neutrophils and monocytes. It is a marker of acute myelogenous leukemias and acute lymphoblastic leukemias. |
| Categories: | Miscellaneous (Human), CD and Related Antigens (Human) |
| Concentration: | 1 mg/ml |
| Storage buffer: | Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4 |
| Storage / stability: | Store at 2-8°C. Do not freeze. Do not use after expiration date stamped on vial label. |
| Background: | Myeloperoxidase (MPO) is a heme enzyme that is localized in azurophilic (primary) granules of myeloid cells and its synthesis occurs at an early stage of differentiation. The mature myeloperoxidase is a tetramer composed of two light (12 kDa) and two heavy (60 kDa) chains. This enzyme uses hydrogen peroxide to oxidize numerous substrates, including serotonin, melatonin or chloride, to produce reactive free radicals that contribute to immune reactions of myeloid cells against pathogens. Myeloperoxidase functions not only in host defense by mediating efficient microbial killing but also can contribute to progressive tissue damage in chronic inflammatory states such as atherosclerosis or acute pancreatitis._x000D_ |
| Purity: | > 95% (by SDS-PAGE) |
| Purification: | Purified by protein-A affinity chromatography |
| Related products: | - Mouse Monoclonal to Neurofilament heavy protein - Mouse Monoclonal to NCK1 - Mouse Monoclonal to Neurofilament heavy protein |
| Shipping condition: | Room temperature |