Cart 0 Product Products (empty)
No products
To be determined Shipping
0,00 € Total
Prices are tax excluded
Product successfully added to your shopping cart
Quantity
Total
There are 0 items in your cart. There is 1 item in your cart.
Total products (tax excl.)
Total shipping (tax excl.) To be determined
Total (tax excl.)
View larger 
Data sheet of Rabbit Polyclonal to Mycobacterium tuberculosis antigen EsaT-6 (Rv3875)
| Brand | Exbio |
| Product type | Primary antibodies |
| Reactivity | Mycobacterium tuberculosis |
| Clonality | Polyclonal |
More info about Rabbit Polyclonal to Mycobacterium tuberculosis antigen EsaT-6 (Rv3875)
| Brand: | Exbio |
| Product no.: | 11-491-C025 |
| Product type: | Primary antibodies |
| Host species: | Rabbit |
| Product name: | Rabbit Polyclonal to Mycobacterium tuberculosis antigen EsaT-6 (Rv3875) |
| Antigen: | Mycobacterium tuberculosis antigen EsaT-6 (Rv3875) |
| Clonality: | Polyclonal |
| Clone: | Polyclonal |
| Immunogen: | EsaT-6 (Rv3875) of Mycobacterium tuberculosis |
| Format: | purified |
| Specificity: | The rabbit polyclonal antibody to EsaT-6 recognizes the EsaT-6 (Rv3875) protein of Mycobacterium tuberculosis and Mycobacterium bovis._x000D_ |
| Categories: | Virology and Microbiology |
| Concentration: | 1 mg/ml |
| Storage buffer: | Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4 |
| Storage / stability: | Store at 2-8°C. Do not freeze. Do not use after expiration date stamped on vial label. |
| Background: | The Mycobacterium tuberculosis antigen EsaT-6 (6 kDa early secretory antigen target EsxA ) causes induction of neutrophil necrosis. This protein acts as a leukocidin, which may facilitate bacterial avoidance of the antimicrobial action of the immune system. |
| Purity: | > 95% (by SDS-PAGE) |
| Purification: | Purified from rabbit serum by affinity chromatography |
| General references: | *Francis RJ, Butler RE, Stewart GR: Mycobacterium tuberculosis ESAT-6 is a leukocidin causing Ca2+ influx, necrosis and neutrophil extracellular trap formation. Cell Death Dis. 2014 Oct 16;5:e1474. , *Arlehamn CS, Sidney J, Henderson R, Greenbaum JA, James EA, Moutaftsi M, Coler R, McKinney DM, Park D, Taplitz R, Kwok WW, Grey H, Peters B, Sette A: Dissecting mechanisms of immunodominance to the common tuberculosis antigens ESAT-6, CFP10, Rv2031c (hspX), Rv2654c (TB7.7), and Rv1038c (EsxJ). J Immunol. 2012 May 15;188(10):5020-31. |
| Related products: | - Rabbit Polyclonal to Mycobacterium tuberculosis antigen Tb7.7 - Rabbit Polyclonal to Mycobacterium tuberculosis antigen GlcB - Rabbit Polyclonal to Mycobacterium tuberculosis antigen Tb10.3 |
| Shipping condition: | Room temperature |