Rabbit Polyclonal to Mycobacterium tuberculosis antigen Acr2 View larger

Rabbit Polyclonal to Mycobacterium tuberculosis antigen Acr2

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Data sheet of Rabbit Polyclonal to Mycobacterium tuberculosis antigen Acr2

BrandExbio
Product typePrimary antibodies
ReactivityMycobacterium tuberculosis
ClonalityPolyclonal

More info about Rabbit Polyclonal to Mycobacterium tuberculosis antigen Acr2

Brand: Exbio
Product no.: 11-188-C100
Product type: Primary antibodies
Host species: Rabbit
Product name: Rabbit Polyclonal to Mycobacterium tuberculosis antigen Acr2
Antigen: Mycobacterium tuberculosis antigen Acr2
Clonality: Polyclonal
Clone: Polyclonal
Immunogen: Recombinant Mycobacterium tuberculosis Acr2 produced in E. coli
Format: purified
Specificity: The rabbit polyclonal antibody to Acr2 reacts with Mycobacterium tuberculosis protein Acr2 (Rv0251c, Hsp20).
Categories: Virology and Microbiology
Concentration: 1 mg/ml
Storage buffer: Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4
Storage / stability: Store at 2-8°C. Do not freeze. Do not use after expiration date stamped on vial label.
Background: The Mycobacterium tuberculosis antigen Acr2 (alpha-crystallin-related protein 2), also known as HrpA or Hsp20, is a small heat shock protein, which forms oligomeric assemblies. Expression of Acr2 is induced by heat shock, oxidative stress, and uptake by macrophages. It evokes a vigorous early immune response.
Purity: > 95% (by SDS-PAGE)
Purification: Purified from rabbit serum by affinity chromatography
General references: *Stewart GR, Newton SM, Wilkinson KA, Humphreys IR, Murphy HN, Robertson BD, Wilkinson RJ, Young DB: The stress-responsive chaperone alpha-crystallin 2 is required for pathogenesis of Mycobacterium tuberculosis. Mol Microbiol. 2005 Feb;55(4):1127-37., *Wilkinson KA, Stewart GR, Newton SM, Vordermeier HM, Wain JR, Murphy HN, Horner K, Young DB, Wilkinson RJ: Infection biology of a novel alpha-crystallin of Mycobacterium tuberculosis: Acr2. J Immunol. 2005 Apr 1;174(7):4237-43., *Kennaway CK, Benesch JL, Gohlke U, Wang L, Robinson CV, Orlova EV, Saibil HR, Keep NH: Dodecameric structure of the small heat shock protein Acr1 from Mycobacterium tuberculosis. J Biol Chem. 2005 Sep 30;280(39):33419-25.
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Shipping condition: Room temperature

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