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Data sheet of Rabbit Polyclonal to Mycobacterium tuberculosis antigen Acr2
| Brand | Exbio |
| Product type | Primary antibodies |
| Reactivity | Mycobacterium tuberculosis |
| Clonality | Polyclonal |
More info about Rabbit Polyclonal to Mycobacterium tuberculosis antigen Acr2
| Brand: | Exbio |
| Product no.: | 11-188-C100 |
| Product type: | Primary antibodies |
| Host species: | Rabbit |
| Product name: | Rabbit Polyclonal to Mycobacterium tuberculosis antigen Acr2 |
| Antigen: | Mycobacterium tuberculosis antigen Acr2 |
| Clonality: | Polyclonal |
| Clone: | Polyclonal |
| Immunogen: | Recombinant Mycobacterium tuberculosis Acr2 produced in E. coli |
| Format: | purified |
| Specificity: | The rabbit polyclonal antibody to Acr2 reacts with Mycobacterium tuberculosis protein Acr2 (Rv0251c, Hsp20). |
| Categories: | Virology and Microbiology |
| Concentration: | 1 mg/ml |
| Storage buffer: | Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4 |
| Storage / stability: | Store at 2-8°C. Do not freeze. Do not use after expiration date stamped on vial label. |
| Background: | The Mycobacterium tuberculosis antigen Acr2 (alpha-crystallin-related protein 2), also known as HrpA or Hsp20, is a small heat shock protein, which forms oligomeric assemblies. Expression of Acr2 is induced by heat shock, oxidative stress, and uptake by macrophages. It evokes a vigorous early immune response. |
| Purity: | > 95% (by SDS-PAGE) |
| Purification: | Purified from rabbit serum by affinity chromatography |
| General references: | *Stewart GR, Newton SM, Wilkinson KA, Humphreys IR, Murphy HN, Robertson BD, Wilkinson RJ, Young DB: The stress-responsive chaperone alpha-crystallin 2 is required for pathogenesis of Mycobacterium tuberculosis. Mol Microbiol. 2005 Feb;55(4):1127-37., *Wilkinson KA, Stewart GR, Newton SM, Vordermeier HM, Wain JR, Murphy HN, Horner K, Young DB, Wilkinson RJ: Infection biology of a novel alpha-crystallin of Mycobacterium tuberculosis: Acr2. J Immunol. 2005 Apr 1;174(7):4237-43., *Kennaway CK, Benesch JL, Gohlke U, Wang L, Robinson CV, Orlova EV, Saibil HR, Keep NH: Dodecameric structure of the small heat shock protein Acr1 from Mycobacterium tuberculosis. J Biol Chem. 2005 Sep 30;280(39):33419-25. |
| Related products: | - Rabbit Polyclonal to Mycobacterium tuberculosis antigen GlcB - Rabbit Polyclonal to Mycobacterium tuberculosis antigen CFP10 (Rv3874) - Rabbit Polyclonal to Mycobacterium tuberculosis antigen EsaT-6 (Rv3875) |
| Shipping condition: | Room temperature |