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Data sheet of Mouse Monoclonal to Lambda light chains
| Brand | Exbio |
| Product type | Primary antibodies |
| Reactivity | Human |
| Clonality | Monoclonal |
More info about Mouse Monoclonal to Lambda light chains
| Brand: | Exbio |
| Product no.: | 11-505-C025 |
| Product type: | Primary antibodies |
| Host species: | Mouse |
| Product name: | Mouse Monoclonal to Lambda light chains |
| Antigen: | Lambda light chains |
| Clonality: | Monoclonal |
| Negative species: | Hamster, Goat, Guinea pig, Rabbit, Sheep |
| Clone: | 4C2 |
| Isotype: | IgG1 |
| Format: | purified |
| Specificity: | The antibody 4C2 reacts with lambda light chains (22.5 kDa) of human immunoglobulin. |
| Categories: | Immunoglobulins (Human) |
| Concentration: | 1 mg/ml |
| Storage buffer: | Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4 |
| Storage / stability: | Store at 2-8°C. Do not freeze. Do not use after expiration date stamped on vial label. |
| Background: | Immunoglobulin classes share the same basic four polypeptide chain structure of two heavy chains (five heavy chains types) and two light chains (kappa, lambda; both having a molecular weight of 22.5kDa). Kappa and lambda consist of a variable region and a constant region and can easily be differentiated by the antigenic properties of the constant region. The ratio of kappa to lambda is 70:30. |
| Purity: | > 95% (by SDS-PAGE) |
| Purification: | Purified by protein-A affinity chromatography |
| Product specific references: | *Os A, Bürgler S, Ribes AP, Funderud A, Wang D, Thompson KM, Tjønnfjord GE, Bogen B, Munthe LA: Chronic lymphocytic leukemia cells are activated and proliferate in response to specific T helper cells. Cell Rep. 2013 Aug 15;4(3):566-77. |
| General references: | *Franklin EC: Structure and function of immunoglobulins. Acta Endocrinol Suppl (Copenh). 1975;194:77-95._x000D_ |
| Related products: | - Mouse Monoclonal to LAT - Mouse Monoclonal to Lamin C - Mouse Monoclonal to LARGE1 |
| Shipping condition: | Room temperature |