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Data sheet of Rabbit Polyclonal to Kinesin
| Brand | Exbio |
| Product type | Primary antibodies |
| Reactivity | Human, Mouse, Porcine, Other not tested |
| Clonality | Polyclonal |
More info about Rabbit Polyclonal to Kinesin
| Brand: | Exbio |
| Product no.: | 11-434-C025 |
| Product type: | Primary antibodies |
| Host species: | Rabbit |
| Product name: | Rabbit Polyclonal to Kinesin |
| Antigen: | Kinesin |
| Clonality: | Polyclonal |
| Clone: | Polyclonal |
| Immunogen: | stalk domain of human kinesin (aa 331-906) expressed in E. coli (FKHC3) |
| Format: | purified |
| Specificity: | The polyclonal antibody detects total level of endogenous kinesin protein. |
| Categories: | Cytoskeleton: Tubulin System (Veterinary), Cytoskeleton: Tubulin System (Rodent), Cytoskeleton: Tubulin System (Human), Cytoskeleton: Microtubular System |
| Concentration: | 1 mg/ml |
| Storage buffer: | Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4 |
| Storage / stability: | Store at 2-8°C. Do not freeze. Do not use after expiration date stamped on vial label. |
| Background: | Kinesin belongs to the group of microtubule-associated motor proteins known to convert chemical energy released from nucleoside triphosphates (preferentially from ATP) into mechanical energy. Conventional kinesin, member of the kinesin superfamily comprising more than 100 proteins, is involved in the anterograde vesicle transport in neuronal cells. Kinesin purified from mammalian brain homogenates is a heterotetramer consisting of two heavy (120 to 130 kDa) and two light chains (60 to 70 kDa), resulting in a molecular mass about 400 kDa. Each heavy chain contains an N-terminal globular motordomain with both a microtubule-binding site and an ATPase active center, stalk region responsible for heavy chain dimerization and finally C-terminal globular tail domain, which is implicated in cargo binding. Light chains may have a regulatory function. |
| Purity: | > 95% (by SDS-PAGE) |
| Purification: | Purified from rabbit serum by affinity chromatography |
| Product specific references: | *Malcova-Janatova I, Richterova V, Draber P, Hasek J: Preparation of human recombinant kinesin heavy chain and epitope mapping of its structural domains. Folia Microbiol (Praha). 2004;49(6):665-70. |
| Related products: | - Rabbit Polyclonal to MRCK alpha - Rabbit Polyclonal to LIME - Rabbit Polyclonal to MEK 1/2 / MAPKK 1/2 |
| Shipping condition: | Room temperature |