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Mouse Monoclonal to IgG (Fc)

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Data sheet of Mouse Monoclonal to IgG (Fc)

BrandExbio
Product typePrimary antibodies
ReactivityHuman, Other not determined
ClonalityMonoclonal

More info about Mouse Monoclonal to IgG (Fc)

Brand: Exbio
Product no.: 11-536-C025
Product type: Primary antibodies
Host species: Mouse
Product name: Mouse Monoclonal to IgG (Fc)
Antigen: IgG (Fc)
Clonality: Monoclonal
Clone: EM-07
Isotype: IgG1
Immunogen: Fusion protein of human IgG Fc fragment.
Format: purified
Specificity: The antibody EM-07 reacts with Fc part of human IgG heavy chain and with isolated Fc fragments. _x000D_
Categories: Immunoglobulins (Human)
Concentration: 1 mg/ml
Storage buffer: Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4
Storage / stability: Store at 2-8°C. Do not freeze. Do not use after expiration date stamped on vial label.
Background: Immunoglobulin G (IgG) is a 150 kDa soluble protein that serves as a major effector molecule of the humoral immune response in man. Its concentration in blood plasma of healthy individuals is approximately 10 g/l, which accounts for about 75% of the total plasma immunoglobulins. IgG has the highest stability of blood immunoglobulins (T1/2 = 21 days) and is able of placental transfer. IgG is secreted by plasma cells at a comparably high rate as other immunoglobulins._x000D_
Purity: > 95% (by SDS-PAGE)
Purification: Purified by protein-A affinity chromatography
General references: *Brinkmann V, Heusser CH: T cell-dependent differentiation of human B cells into IgM, IgG, IgA, or IgE plasma cells: high rate of antibody production by IgE plasma cells, but limited clonal expansion of IgE precursors. Cell Immunol. 1993 Dec;152(2):323-32._x000D_ , *Balogh Z, Merétey K, Falus A, Bozsóky S: Serological abnormalities in juvenile chronic arthritis: a review of 46 cases. Ann Rheum Dis. 1980 Apr;39(2):129-34._x000D_ , *Franklin EC: Structure and function of immunoglobulins. Acta Endocrinol Suppl (Copenh). 1975;194:77-95._x000D_ , *Fuller JM, Keyser JW: Serum immunoglobulins after surgical operation. Clin Chem. 1975 May;21(6):667-71._x000D_
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