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Data sheet of Mouse Monoclonal to IgG (Fab)
| Brand | Exbio |
| Product type | Primary antibodies |
| Reactivity | Human |
| Clonality | Monoclonal |
More info about Mouse Monoclonal to IgG (Fab)
| Brand: | Exbio |
| Product no.: | 11-319-C025 |
| Product type: | Primary antibodies |
| Host species: | Mouse |
| Product name: | Mouse Monoclonal to IgG (Fab) |
| Antigen: | IgG (Fab) |
| Clonality: | Monoclonal |
| Clone: | 4A11 |
| Isotype: | IgG2b |
| Immunogen: | Purified human IgG. |
| Format: | purified |
| Specificity: | The antibody 4A11 reacts with Fab fragment of human IgG. _x000D_ |
| Categories: | Immunoglobulins (Human) |
| Concentration: | 1 mg/ml |
| Storage buffer: | Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4 |
| Storage / stability: | Store at 2-8°C. Do not freeze. Do not use after expiration date stamped on vial label. |
| Background: | Immunoglobulin G (IgG) is a 150 kDa soluble protein that serves as a major effector molecule of the humoral immune response in man. Its concentration in blood plasma of healthy individuals is approximately 10 g/l, which accounts for about 75% of the total plasma immunoglobulins. IgG has the highest stability of blood immunoglobulins (T1/2 = 21 days) and is able of placental transfer. IgG is secreted by plasma cells at a comparably high rate as other immunoglobulins. |
| Purity: | > 95% (by SDS-PAGE) |
| Purification: | Purified by precipitation and chromatography |
| General references: | *Brinkmann V, Heusser CH: T cell-dependent differentiation of human B cells into IgM, IgG, IgA, or IgE_x000D_ plasma cells: high rate of antibody production by IgE plasma cells, but limited clonal expansion of IgE precursors. Cell Immunol. 1993 Dec;152(2):323-32._x000D_ _x000D_ _x000D_ , *Balogh Z, Merétey K, Falus A, Bozsóky S: Serological abnormalities in juvenile chronic arthritis: a review of 46 cases. Ann Rheum Dis. 1980 Apr;39(2):129-34._x000D_ _x000D_ _x000D_ , *Fuller JM, Keyser JW: Serum immunoglobulins after surgical operation. Clin Chem. 1975 May;21(6):667-71._x000D_ _x000D_ _x000D_ , *Franklin EC: Structure and function of immunoglobulins. Acta Endocrinol Suppl (Copenh). 1975;194:77-95._x000D_ _x000D_ _x000D_ |
| Related products: | - Mouse Monoclonal to Ikaros - Mouse Monoclonal to IgG (Fc) - Mouse Monoclonal to IgM |
| Shipping condition: | Room temperature |