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Data sheet of Mouse Monoclonal to IgA
| Brand | Exbio |
| Product type | Primary antibodies |
| Reactivity | Human |
| Clonality | Monoclonal |
More info about Mouse Monoclonal to IgA
| Brand: | Exbio |
| Product no.: | 11-322-C025 |
| Product type: | Primary antibodies |
| Host species: | Mouse |
| Product name: | Mouse Monoclonal to IgA |
| Antigen: | IgA |
| Clonality: | Monoclonal |
| Clone: | AD3 |
| Isotype: | IgG1 |
| Immunogen: | Purified human IgA. |
| Format: | purified |
| Specificity: | The antibody AD3 reacts with alpha-chain of human IgA1 and IgA2. |
| Categories: | Immunoglobulins (Human) |
| Concentration: | 1 mg/ml |
| Storage buffer: | Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4 |
| Storage / stability: | Store at 2-8°C. Do not freeze. Do not use after expiration date stamped on vial label. |
| Background: | Immunoglobulin A (IgA) is the major immunoglobulin class in body secretions that protects against infections of the mucous membranes lining the mouth, airways, and digestive tract. Its serum concentration is approximately 0.2 g/l and biological survival (T1/2 in plasma) 6 days. Plasma IgA is predominantly monomeric (160 kDa) and of the IgA1 subclass, and is mostly produced in the bone marrow. Over half of IgA produced by the intestinal lamina propria plasmocytes is in oligomeric form and 35% of it is IgA2. |
| Purity: | > 95% (by SDS-PAGE) |
| Purification: | Purified by precipitation and chromatography |
| General references: | *Jonard PP, Rambaud JC, Dive C, Vaerman JP, Galian A, Delacroix DL: Secretion of immunoglobulins and plasma proteins from the jejunal mucosa. Transport rate and origin of polymeric immunoglobulin A. J Clin Invest. 1984 Aug;74(2):525-35._x000D_ _x000D_ _x000D_ , *Balogh Z, Merétey K, Falus A, Bozsóky S: Serological abnormalities in juvenile chronic arthritis: a review of 46 cases. Ann Rheum Dis. 1980 Apr;39(2):129-34._x000D_ , *Fuller JM, Keyser JW: Serum immunoglobulins after surgical operation. Clin Chem. 1975 May;21(6):667-71._x000D_ , *Franklin EC: Structure and function of immunoglobulins. Acta Endocrinol Suppl (Copenh). 1975;194:77-95._x000D_ |
| Related products: | - Mouse Monoclonal to IgG (Fab) - Mouse Monoclonal to IgD - Mouse Monoclonal to IgE |
| Shipping condition: | Room temperature |