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Mouse Monoclonal to HLA-G

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Data sheet of Mouse Monoclonal to HLA-G

BrandExbio
Product typePrimary antibodies
ReactivityHuman
ClonalityMonoclonal

More info about Mouse Monoclonal to HLA-G

Brand: Exbio
Product no.: 11-499-C025
Product type: Primary antibodies
Host species: Mouse
Product name: Mouse Monoclonal to HLA-G
Antigen: HLA-G
Clonality: Monoclonal
Clone: 4H84
Isotype: IgG1
Immunogen: amino acids 61-83 of HLA-G of human origin
Format: purified
Specificity: The antibody 4H84 recognizes HLA-G molecule (39 kDa). HLA-G belongs to the MHC Class I molecules (MHC Class Ib; nonclassical) and it is expressed on the surface of trophoblast cells.
_x000D_ This product is for research and in vitro experimental use only. It is not to be used for any other commercial purpose. Use of this product to produce products for sale or for therapeutic or drug discovery purposes is prohibited. In order to obtain a license to use this product for commercial purposes, contact The Regents of the Univesity of California._x000D_ _x000D_
Categories: MHC (Major Histocompatibility Complex) and Related Antigens (Human)
Concentration: 1 mg/ml
Storage buffer: Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4
Storage / stability: Store at 2-8°C. Do not freeze. Do not use after expiration date stamped on vial label.
Purity: > 95% (by SDS-PAGE)
Purification: Purified by protein-A affinity chromatography
Product specific references: *And many other., *Gonen-Gross T, Achdout H, Arnon TI, Gazit R, Stern N, Horejsí V, Goldman-Wohl D, Yagel S, Mandelboim O: The CD85J/leukocyte inhibitory receptor-1 distinguishes between conformed and beta 2-microglobulin-free HLA-G molecules. J Immunol. 2005 Oct 15;175(8):4866-74._x000D_ _x000D_ _x000D_ , *Juch H, Blaschitz A, Daxbock C, Rueckert C, Kofler K, Dohr G: A novel sandwich ELISA for alpha1 domain based detection of soluble HLA-G heavy chains. J Immunol Methods. 2005 Dec 20;307(1-2):96-106._x000D_ , *Barrier BF, Kendall BS, Sharpe-Timms KL, Kost ER: Characterization of human leukocyte antigen-G (HLA-G) expression in endometrial adenocarcinoma. Gynecol Oncol. 2006 Oct;103(1):25-30. _x000D_ , *Polakova K, Kuba D, Russ G: The 4H84 monoclonal antibody detecting beta2m free nonclassical HLA-G molecules also binds to free heavy chains of classical HLA class I antigens present on activated lymphocytes. Hum Immunol. 2004 Feb;65(2):157-62. _x000D_ , *Polakova K, Krcova M, Kuba D, Russ G: Analysis of HLA-G expression in malignant hematopoetic cells from leukemia_x000D_ patients. Leuk Res. 2003 Jul;27(7):643-8. _x000D_ , *Menier C, Saez B, Horejsi V, Martinozzi S, Krawice-Radanne I, Bruel S, Le Danff C, Reboul M, Hilgert I, Rabreau M, Larrad ML, Pla M, Carosella ED, Rouas-Freiss N: Characterization of monoclonal antibodies recognizing HLA-G or HLA-E: new tools to analyze the expression of nonclassical HLA class I molecules. Hum Immunol. 2003 Mar;64(3):315-26. _x000D_ , *Urosevic M, Kurrer MO, Kamarashev J, Mueller B, Weder W, Burg G, Stahel RA, Dummer R, Trojan A: Human leukocyte antigen G up-regulation in lung cancer associates with high-grade histology, human leukocyte antigen class I loss and interleukin-10 production. Am J Pathol. 2001 Sep;159(3):817-24. _x000D_ , *Blaschitz A, Hutter H, Dohr G: HLA Class I protein expression in the human placenta. Early Pregnancy. 2001 Jan;5(1):67-9. _x000D_ _x000D_ , *Paul P, Rouas-Freiss N, Khalil-Daher I, Moreau P, Riteau B, Le Gal FA, Avril MF, Dausset J, Guillet JG, Carosella ED: HLA-G expression in melanoma: a way for tumor cells to escape from immunosurveillance. Proc Natl Acad Sci U S A. 1998 Apr 14;95(8):4510-5. _x000D_
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Shipping condition: Room temperature

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