Brand | Exbio |
Product type | Primary antibodies |
Reactivity | Human |
Clonality | Monoclonal |
Brand: | Exbio |
Product no.: | 11-291-C025 |
Product type: | Primary antibodies |
Host species: | Mouse |
Product name: | Mouse Monoclonal to HLA-G |
Antigen: | HLA-G |
Clonality: | Monoclonal |
Clone: | MEM-G/1 |
Isotype: | IgG1 |
Immunogen: | Denatured bacterially expressed recombinant human HLA-G heavy chain. |
Format: | purified |
Specificity: | The antibody MEM-G/1 reacts with denaturated HLA-G heavy chain. HLA-G belongs to the MHC Class I molecules (MHC Class Ib; nonclassical) and it is expressed on the surface of trophoblast cells. |
Categories: | MHC (Major Histocompatibility Complex) and Related Antigens (Human) |
Concentration: | 1 mg/ml |
Storage buffer: | Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4 |
Storage / stability: | Store at 2-8°C. Do not freeze. Do not use after expiration date stamped on vial label. |
Purity: | > 95% (by SDS-PAGE) |
Purification: | Purified by protein-A affinity chromatography |
Product specific references: | *Amiot L, Vu N, Rauch M, Helgoualc'h AL, Chalmel F, Gascan H, Turlin B, Guyader D, Samson M: Expression of HLA-G by mast cells is associated with hepatitis C virus-induced liver fibrosis. J Hepatol. 2013 Sep 11. pii: S0168-8278(13), *Hurks HM, Valter MM, Wilson L, Hilgert I, van den Elsen PJ, Jager MJ: Uveal melanoma: no expression of HLA-G. Invest Ophthalmol Vis Sci. 2001 Dec;42(13):3081-4._x000D_ _x000D_ _x000D_ , *Gonen-Gross T, Achdout H, Arnon TI, Gazit R, Stern N, Horejsà V, Goldman-Wohl D, Yagel S, Mandelboim O: The CD85J/leukocyte inhibitory receptor-1 distinguishes between conformed and beta 2-microglobulin-free HLA-G molecules. J Immunol. 2005 Oct 15;175(8):4866-74._x000D_ , *Fournel S, Huc X, Aguerre-Girr M, Solier C, Legros M, Praud-Brethenou C, Moussa M, Chaouat G, Berrebi A, Bensussan A, Lenfant F, Le Bouteiller P: Comparative reactivity of different HLA-G monoclonal antibodies to soluble HLA-G molecules. Tissue Antigens. 2000 Jun;55(6):510-8. _x000D_ , *Shih IM, Kurman RJ: p63 expression is useful in the distinction of epithelioid trophoblastic and placental site trophoblastic tumors by profiling trophoblastic subpopulations. Am J Surg Pathol. 2004 Sep;28(9):1177-83. _x000D_ , *Boyson JE, Erskine R, Whitman MC, Chiu M, Lau JM, Koopman LA, Valter MM, Angelisova P, Horejsi V, Strominger JL: Disulfide bond-mediated dimerization of HLA-G on the cell surface. Proc Natl Acad Sci U S A. 2002 Dec 10;99(25):16180-5. Epub 2002 Nov 26. _x000D_ , *Frumento G, Franchello S, Palmisano GL, Nicotra MR, Giacomini P, Loke YW, Geraghty DE, Maio M, Manzo C, Natali PG, Ferrara GB: Melanomas and melanoma cell lines do not express HLA-G, and the expression cannot be induced by gammaIFN treatment. Tissue Antigens. 2000 Jul;56(1):30-7. _x000D_ |
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Shipping condition: | Room temperature |