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Mouse Monoclonal to Cytokeratin 10+13

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Data sheet of Mouse Monoclonal to Cytokeratin 10+13

BrandExbio
Product typePrimary antibodies
ReactivityHuman, Feline (Cat), Other species Not tested
ClonalityMonoclonal

More info about Mouse Monoclonal to Cytokeratin 10+13

Brand: Exbio
Product no.: 11-478-C025
Product type: Primary antibodies
Host species: Mouse
Product name: Mouse Monoclonal to Cytokeratin 10+13
Antigen: Cytokeratin 10+13
Clonality: Monoclonal
Clone: DE-K13
Isotype: IgG2a
Immunogen: Cytoskeletal preparation extracted from human ectocervical epithelium. _x000D_
Format: purified
Specificity: The antibody DE-K13 reacts with Cytokeratin 10 (56.5 kDa) and Cytokeratin 13 (53 kDa). Cytokeratins are a member of intermediate filaments subfamily represented in epithelial tissues. DE-K13 recognizes only Cytokeratin 13 on formalin-fixed, paraffin-embedded tissue sections.
Categories: Cytoskeleton: Intermediate Filaments (Veterinary), Cytoskeleton: Intermediate Filaments (Human), Cytoskeleton: Intermediate Filaments
Concentration: 1 mg/ml
Storage buffer: Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4
Storage / stability: Store at 2-8°C. Do not freeze. Do not use after expiration date stamped on vial label.
Background: Cytokeratins are a subfamily of intermediate filaments and characterized by remarkable biochemical diversity. Cytokeratins are represented in epithelial tissues by at least 20 different polypeptides, molecular weight between 40 kDa and 68 kDa. The individual cytokeratin polypeptides are designated 1 to 20 and divided into the type I (acidic cytokeratins 9-20) and type II (basic to neutral cytokeratins 1-8) families.Cytokeratins 10 and 13 both belong to type I family (acidic cytokeratins).
Purity: > 95% (by SDS-PAGE)
Purification: Purified by protein-A affinity chromatography
Product specific references: *Ivanyi D, Minke JM, Hageman C, Groeneveld E, van Doornewaard G: Patterns of expression of feline cytokeratins in healthy epithelia and mammary carcinoma cells. Am J Vet Res. 1992 Mar;53(3):304-14. , *Ivanyi D, Minke JM, Hageman C, Groeneveld E, van Doornewaard G, Misdorp W: Cytokeratins as markers of initial stages of squamous metaplasia in feline mammary carcinomas. Am J Vet Res. 1993 Jul;54(7):1095-102. , *Kozaki M, Nakamura Y, Iguchi M, Kano R, Watanabe S, Fujiwara K, Hasegawa A: Immunohistochemical analysis of cytokeratin expression in dog skin. J Vet Med Sci. 2001 Jan;63(1):1-4. _x000D_
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Shipping condition: Room temperature

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