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Data sheet of Mouse Monoclonal to CRP
| Brand | Exbio |
| Product type | Primary antibodies |
| Reactivity | Human |
| Clonality | Monoclonal |
| Host species | Mouse |
| Applications | ELISA |
More info about Mouse Monoclonal to CRP
| Brand: | Exbio |
| Product no.: | 11-538-C100 |
| Product name: | Mouse Monoclonal to CRP |
| Antigen: | CRP |
| Clonality: | Monoclonal |
| Clone: | C6 |
| Isotype: | IgG2a |
| Immunogen: | Purified human CRP |
| Format: | purified |
| Specificity: | The antibody C6 recognizes human CRP, an 117 kDa acute phase protein; it recognizes the antigen both in the presence and in the absence (samples containing EDTA) of Ca2+. |
| Categories: | Transcription Regulation & Nuclear Proteins, Transcription Regulation & Nuclear Proteins (Human), Serum & Plasma Proteins (Human) |
| Concentration: | 1 mg/ml |
| Storage buffer: | Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4 |
| Storage / stability: | Store at 2-8°C. Do not freeze. Do not use after expiration date stamped on vial label. |
| Background: | The C-reactive protein (CRP) is a cyclic pentameric pentraxin family acute phase protein compound of five identical noncovalently bound nonglycosylated subunits (each subunit 24 kDa; physiologic CRP molecule 117,5 kDa). CRP is produced by the liver and its plasma levels rise dramatically during inflammatory processes occuring in the body. CRP is an initiator of classical complement cascade, binds to several nuclear components (chromatin, histones, etc.) and is also believed to play an important role in innate immunity. Patients with elevated basal levels of CRP are at increased risk for hypertension and cardiovascular disease. |
| Purity: | > 95% (by SDS-PAGE) |
| Purification: | Purified from ascites by protein-A affinity chromatography. |
| Product specific references: | *Meyer MH, Hartmann M, Krause HJ, Blankenstein G, Mueller-Chorus B, Oster J, Miethe P, Keusgen M: CRP determination based on a novel magnetic biosensor. Biosens Bioelectron. 2007 Jan 15;22(6):973-9. |
| General references: | *van der Harst P, Voors AA, Volbeda M, Buikema H, van Veldhuisen DJ, van Gilst WH: Usefulness of preoperative C-reactive protein and soluble intercellular adhesion molecule-1 level for predicting future cardiovascular events after coronary artery bypass grafting. Am J Cardiol. 2006 Jun 15;97(12):1697-701. , *Meyer MH, Hartmann M, Krause HJ, Blankenstein G, Mueller-Chorus B, Oster J, Miethe P, Keusgen M: CRP determination based on a novel magnetic biosensor. Biosens Bioelectron. 2007 Jan 15;22(6):973-9. |
| Shipping condition: | Room temperature |