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Data sheet of Mouse Monoclonal to CPNE7
| Brand | Exbio |
| Product type | Primary antibodies |
| Reactivity | Human, Other not determined |
| Clonality | Monoclonal |
More info about Mouse Monoclonal to CPNE7
| Brand: | Exbio |
| Product no.: | 11-542-C025 |
| Product type: | Primary antibodies |
| Host species: | Mouse |
| Product name: | Mouse Monoclonal to CPNE7 |
| Antigen: | CPNE7 |
| Clonality: | Monoclonal |
| Clone: | CPNE7-01 |
| Isotype: | IgG |
| Immunogen: | Bacterially produced GST-fused C terminus of human CPNE7._x000D_ |
| Format: | purified |
| Specificity: | The antibody CPNE7-01 recognizes C terminus of human CPNE7, a calcium-binding cytoplasmic protein expressed mainly in brain._x000D_ |
| Categories: | Phosphorylation (Kinases, Phosphatases, Phosphotyrosine), Calcium Signaling, Phosphorylation (Kinases, Phosphatases, Phosphotyrosine) (Human), Calcium Signaling (Human) |
| Concentration: | 1 mg/ml |
| Storage buffer: | Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4 |
| Storage / stability: | Store at 2-8°C. Do not freeze. Do not use after expiration date stamped on vial label. |
| Background: | CPNE7 (copine VII) is a member of highly conserved copine family, which is composed of calcium-dependent membrane-binding proteins containing two N-terminal C domains and a C-terminal A domain (von Willenbrand domain). There is an evidence that copines (at least copine III) may represent a novel unconventional kinase family. CPNE7 is expressed mainly in brain, but also in duodenum, jejunum, thymus and testes._x000D_ |
| Purity: | > 95% (by SDS-PAGE) |
| Purification: | Purified by protein-A affinity chromatography |
| General references: | *Cowland JB, Carter D, Bjerregaard MD, Johnsen AH, Borregaard N, Lollike K: Tissue expression of copines and isolation of copines I and III from the cytosol of human neutrophils. J Leukoc Biol. 2003 Sep;74(3):379-88._x000D_ , *Savino M, d'Apolito M, Centra M, van Beerendonk HM, Cleton-Jansen AM, Whitmore SA, Crawford J, Callen DF, Zelante L, Savoia A: Characterization of copine VII, a new member of the copine family, and its exclusion as a candidate in sporadic breast cancers with loss of heterozygosity at 16q24.3. Genomics. 1999 Oct 15;61(2):219-26., *Caudell EG, Caudell JJ, Tang CH, Yu TK, Frederick MJ, Grimm EA: Characterization of human copine III as a phosphoprotein with associated kinase activity. Biochemistry. 2000 Oct 24;39(42):13034-43._x000D_ |
| Related products: | - Mouse Monoclonal to Cyclin D1 - Mouse Monoclonal to CRP - Mouse Monoclonal to Csk |
| Shipping condition: | Room temperature |