Brand | Exbio |
Product type | Primary antibodies |
Reactivity | Human |
Clonality | Monoclonal |
Brand: | Exbio |
Product no.: | 11-789-C025 |
Product type: | Primary antibodies |
Host species: | Mouse |
Product name: | Mouse Monoclonal to CD56 / NCAM |
Antigen: | CD56 |
Clonality: | Monoclonal |
Clone: | LT56 |
Isotype: | IgG2a |
Immunogen: | Cell line KG1a |
Format: | purified |
Specificity: | The mouse monoclonal antibody LT56 recognizes CD56 (NCAM), a transmembrane glycoprotein expressed ubiquitously in the nervous system and found also on T cells and NK cells._x000D_ _x000D_ HLDA 10 |
Categories: | CD and Related Antigens (Human) |
Concentration: | 1 mg/ml |
Storage buffer: | Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4 |
Storage / stability: | Store at 2-8°C. Do not freeze. Do not use after expiration date stamped on vial label. |
Background: | CD56 (NCAM, neural cell adhesion molecule) is a transmembrane glycoprotein of immunoglobulin family serving as adhesive molecule which is ubiquitously expressed in nervous system, usually as 120 kDa, 140 kDa or 180 kDa isoform, and it is also found on T cells and NK cells. Polysialic modification results in reduction of CD56-mediated cell adhesion and is involved in cell migration, axonal growth, pathfinding and synaptic plasticity. CD56 is a widely used neuroendocrine marker with a high sensitivity for neuroendocrine tumours and ovarian granulosa cell tumours. |
Purity: | > 95% (by SDS-PAGE) |
Purification: | Purified by protein-A affinity chromatography |
Related products: | - Mouse Monoclonal to CD6 - Mouse Monoclonal to CD57 - Mouse Monoclonal to CD59 / Protectin |
Shipping condition: | Room temperature |