Cart 0 Product Products (empty)
No products
To be determined Shipping
0,00 € Total
Prices are tax excluded
Product successfully added to your shopping cart
Quantity
Total
There are 0 items in your cart. There is 1 item in your cart.
Total products (tax excl.)
Total shipping (tax excl.) To be determined
Total (tax excl.)
Data sheet of Mouse Monoclonal to CD173
| Brand | Exbio |
| Product type | Primary antibodies |
| Reactivity | Human |
| Clonality | Monoclonal |
| Host species | Mouse |
| Applications | FC |
More info about Mouse Monoclonal to CD173
| Brand: | Exbio |
| Product no.: | 99-594-L001 |
| Product name: | Mouse Monoclonal to CD173 |
| Antigen: | CD173 |
| Clonality: | Monoclonal |
| Clone: | MEM-198 |
| Isotype: | IgM |
| Immunogen: | Human thrombocytes |
| Format: | culture supernatant |
| Specificity: | The antibody MEM-198 reacts with CD173 (H2), a saccharide antigen expressed mainly during early hematopoiesis; it is also expressed on endothelial cells. HLDA 7, WS code: 70284 |
| Categories: | Blood Group Antigens (Human), CD and Related Antigens (Human) |
| Storage / stability: | Store at 2-8°C. Do not use after expiration date stamped on vial label. Do not freeze. |
| Background: | CD173 (blood group antigen H2) is a fucosylated saccharide (Fuc-alpha-1-2-Gal-beta-1-4-GlcNAc-beta) generated by beta-D-galactoside 2-alpha-L-fucosyltransferase (FUT1). CD173 belongs to markers of early hematopoiesis; it is expressed mainly on CD34-positive hematopoietic progenitor cells. CD173 is a precursor structure of CD174 (Lewis Y) and is also structurally related to CD15 (Lewis X). On endothelial cells CD173 and CD174 are concentrated on pseudopodial extensions responsible for initial contacts between endothelial cells. |
| Preparation: | The hybridoma culture supernatant is 4 x concentrated by ultrafiltration using 100 kDa-cut off membrane. |
| Product specific references: | *Leukocyte Typing VII., Mason D.Y. et al. (Eds.), Oxford University Press (2002). |
| General references: | *Moehler TM, Sauer S, Witzel M, Andrulis M, Garcia-Vallejo JJ, Grobholz R, Willhauck-Fleckenstein M, Greiner A, Goldschmidt H, Schwartz-Albiez R: Involvement of alpha 1-2-fucosyltransferase I (FUT1) and surface-expressed Lewis(y) (CD174) in first endothelial cell-cell contacts during angiogenesis. J Cell Physiol. 2008 Apr;215(1):27-36., *Cao Y, Merling A, Karsten U, Schwartz-Albiez R: The fucosylated histo-blood group antigens H type 2 (blood group O, CD173) and Lewis Y (CD174) are expressed on CD34+ hematopoietic progenitors but absent on mature lymphocytes. Glycobiology. 2001 Aug;11(8):677-83. |
| Shipping condition: | Room temperature |