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Mouse Monoclonal to CD165

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Data sheet of Mouse Monoclonal to CD165

BrandExbio
Product typePrimary antibodies
ReactivityHuman
ClonalityMonoclonal

More info about Mouse Monoclonal to CD165

Brand: Exbio
Product no.: 11-165-C100
Product type: Primary antibodies
Host species: Mouse
Product name: Mouse Monoclonal to CD165
Antigen: CD165
Clonality: Monoclonal
Clone: SN2
Isotype: IgG1
Immunogen: CD165 purified from human Molt-4 cell line
Format: purified
Specificity: The mouse monoclonal antibody SN2, also known as SN2 N6-D11, recognizes CD165, an approximately 37-42 kDa transmembrane glycoprotein expressed mainly on leukemic T cells, double positive and double negative thymocytes (CD4-CD8-, CD4+CD8+), and platelets._x000D_
_x000D_ HLDA VI: WS Code N-L099
Categories: CD and Related Antigens (Human)
Concentration: 1 mg/ml
Storage buffer: Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4
Storage / stability: Store at 2-8°C. Do not freeze. Do not use after expiration date stamped on vial label.
Background: CD165 is a poorly characterized transmembrane protein highly expressed on platelets and many leukemic T cell lines. At lower level it is expressed on a proportion of circulating T cells and monocytes, on thymic epithelium, fibroblasts, epidermal keratinocytes, pancreatic islet cells, and some neurons. It might have a role in adhesion between thymocytes and thymic epithelial cells and it can be used as a marker for tumor progression.
Purity: > 95% (by SDS-PAGE)
Purification: Purified from cell culture supernatant by protein-A affinity chromatography.
Product specific references: *Seon BK: Specific killing of human T-leukemia cells by immunotoxins prepared with ricin A chain and monoclonal anti-human T-cell leukemia antibodies. Cancer Res. 1984 Jan;44(1):259-64., *Seon BK, Negoro S, Barcos MP, Tebbi CK, Chervinsky D, Fukukawa T: Monoclonal antibody SN2 defining a human T cell leukemia-associated cell surface glycoprotein. J Immunol. 1984 Apr;132(4):2089-95.
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Shipping condition: Room temperature

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