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Data sheet of Mouse Monoclonal to Blood Group Lewis a
| Brand | Exbio |
| Product type | Primary antibodies |
| Reactivity | Other not tested, Human |
| Clonality | Monoclonal |
More info about Mouse Monoclonal to Blood Group Lewis a
| Brand: | Exbio |
| Product no.: | 11-385-C025 |
| Product type: | Primary antibodies |
| Host species: | Mouse |
| Product name: | Mouse Monoclonal to Blood Group Lewis a |
| Antigen: | Blood Group Lewis a |
| Clonality: | Monoclonal |
| Clone: | 7LE |
| Isotype: | IgG1 |
| Immunogen: | Mucin isolated by size-exclusion chromatography from an ovarian cyst fluid (pure endocervical type according to the Fenoglio´s classification). |
| Format: | purified |
| Specificity: | The antibody 7LE recognizes Lewisa blood group antigen, a carbohydrate determinant carried on both glycolipids and glycoproteins, expressed in colonic epithelial cells. Lewisa may be useful for detection of gastrointestinal, pancreatic and colorectal tumors. |
| Categories: | Blood Group Antigens (Human) |
| Concentration: | 1 mg/ml |
| Storage buffer: | Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4 |
| Storage / stability: | Store at 2-8°C. Do not freeze. Do not use after expiration date stamped on vial label. |
| Purity: | > 95% (by SDS-PAGE) |
| Purification: | Purified by protein-A affinity chromatography |
| Product specific references: | *Creuzot-Garcher C, Guerzider V, Assem M, Bron AM, Delannoy P, Bara J: Alteration of sialyl Lewis epitope expression in pterygium. Invest Ophthalmol Vis Sci. 1999 Jul;40(8):1631-6. _x000D_ , *First International Workshop on Monoclonal Antibodies Against Red Blood Cell and Related Antigens. Paris, September 21-24, 1987. Vol. II: Other blood group systems. |
| General references: | *Torrado J, Correa P, Ruiz B, Bernardi P, Zavala D, Bara J: Lewis antigen alterations in gastric cancer precursors._x000D_ Gastroenterology. 1992 Feb;102(2):424-30. _x000D_ , *Bara J, Gautier R, Le Pendu J, Oriol R: Immunochemical characterization of mucins. Polypeptide (M1) and polysaccharide (A and Leb) antigens. Biochem J. 1988 Aug 15;254(1):185-93. _x000D_ |
| Related products: | - Mouse Monoclonal to CD10 / CALLA - Mouse Monoclonal to Blood Group Lewis b - Mouse Monoclonal to Brg1 |
| Shipping condition: | Room temperature |