Brand | Exbio |
Product type | Primary antibodies |
Reactivity | Other not tested, Human |
Clonality | Monoclonal |
Brand: | Exbio |
Product no.: | 11-385-C025 |
Product type: | Primary antibodies |
Host species: | Mouse |
Product name: | Mouse Monoclonal to Blood Group Lewis a |
Antigen: | Blood Group Lewis a |
Clonality: | Monoclonal |
Clone: | 7LE |
Isotype: | IgG1 |
Immunogen: | Mucin isolated by size-exclusion chromatography from an ovarian cyst fluid (pure endocervical type according to the Fenoglio´s classification). |
Format: | purified |
Specificity: | The antibody 7LE recognizes Lewisa blood group antigen, a carbohydrate determinant carried on both glycolipids and glycoproteins, expressed in colonic epithelial cells. Lewisa may be useful for detection of gastrointestinal, pancreatic and colorectal tumors. |
Categories: | Blood Group Antigens (Human) |
Concentration: | 1 mg/ml |
Storage buffer: | Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4 |
Storage / stability: | Store at 2-8°C. Do not freeze. Do not use after expiration date stamped on vial label. |
Purity: | > 95% (by SDS-PAGE) |
Purification: | Purified by protein-A affinity chromatography |
Product specific references: | *Creuzot-Garcher C, Guerzider V, Assem M, Bron AM, Delannoy P, Bara J: Alteration of sialyl Lewis epitope expression in pterygium. Invest Ophthalmol Vis Sci. 1999 Jul;40(8):1631-6. _x000D_ , *First International Workshop on Monoclonal Antibodies Against Red Blood Cell and Related Antigens. Paris, September 21-24, 1987. Vol. II: Other blood group systems. |
General references: | *Torrado J, Correa P, Ruiz B, Bernardi P, Zavala D, Bara J: Lewis antigen alterations in gastric cancer precursors._x000D_ Gastroenterology. 1992 Feb;102(2):424-30. _x000D_ , *Bara J, Gautier R, Le Pendu J, Oriol R: Immunochemical characterization of mucins. Polypeptide (M1) and polysaccharide (A and Leb) antigens. Biochem J. 1988 Aug 15;254(1):185-93. _x000D_ |
Related products: | - Mouse Monoclonal to CD10 / CALLA - Mouse Monoclonal to Blood Group Lewis b - Mouse Monoclonal to Brg1 |
Shipping condition: | Room temperature |