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Data sheet of Mouse Monoclonal to alpha-Fetoprotein
| Brand | Exbio |
| Product type | Primary antibodies |
| Reactivity | Other not tested, Human |
| Clonality | Monoclonal |
More info about Mouse Monoclonal to alpha-Fetoprotein
| Brand: | Exbio |
| Product no.: | 11-259-C025 |
| Product type: | Primary antibodies |
| Host species: | Mouse |
| Product name: | Mouse Monoclonal to alpha-Fetoprotein |
| Antigen: | alpha-Fetoprotein |
| Clonality: | Monoclonal |
| Clone: | AFP-01 |
| Isotype: | IgG1 |
| Immunogen: | purified alpha-Fetoprotein |
| Format: | purified |
| Specificity: | The antibody AFP-01 reacts with human alpha-Fetoprotein (AFP), a 70 kDa oncofetal antigen. AFP is a major fetal plasma protein, but is not present in healthy adult tissues. Elevated AFP concentrations in adult plasma may be an early marker of hepatocellular carcinoma or teratoblastoma, while high concentrations in amniotic fluid may indicate severe congenital defects of a fetus. |
| Categories: | Serum & Plasma Proteins (Human) |
| Concentration: | 1 mg/ml |
| Storage buffer: | Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4 |
| Storage / stability: | Store at 2-8°C. Do not freeze. Do not use after expiration date stamped on vial label. |
| Purity: | > 95% (by SDS-PAGE) |
| Purification: | Purified by precipitation methods |
| Product specific references: | *Cermák L, SÃmová S, Pintzas A, Horejsà V, Andera L: Molecular mechanisms involved in CD43-mediated apoptosis of TF-1 cells. Roles of transcription Daxx expression, and adhesion molecules. J Biol Chem. 2002 Mar 8;277(10):7955-61. , *Cavin LG, Venkatraman M, Factor VM, Kaur S, Schroeder I, Mercurio F, Beg AA, Thorgeirsson SS, Arsura M: Regulation of alpha-fetoprotein by nuclear factor-kappaB protects hepatocytes from tumor necrosis factor-alpha cytotoxicity during fetal liver development and hepatic oncogenesis. Cancer Res. 2004 Oct 1;64(19):7030-8. _x000D_ , *Stefanova I, Horejsi V, Kristofova H, Angelisova P, Zizkovsky V, Hilgert I: Monoclonal antibodies against human alpha-fetoprotein. Exploitation of an unusual calcium-dependent interaction with the antigen for analytical and preparative purposes. J Immunol Methods. 1988 Jun 28;111(1):67-73. _x000D_ |
| Related products: | - Mouse Monoclonal to ARHGEF4 / ASEF1 - Mouse Monoclonal to alpha-tubulin - Mouse Monoclonal to ARAP1 / centaurin |
| Shipping condition: | Room temperature |