HLA-DP monoclonal antibody, clone SPM421 View larger

HLA-DP monoclonal antibody, clone SPM421

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289,00 € tax excl.

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Data sheet of HLA-DP monoclonal antibody, clone SPM421

BrandAbnova
Product typePrimary antibodies
ReactivityHuman
ClonalityMonoclonal
Host speciesMouse
ApplicationsIHC-P,IF,Flow Cyt

More info about HLA-DP monoclonal antibody, clone SPM421

Product description: Mouse monoclonal antibody raised against native human HLA-DP.
Clone: SPM421
Isotype: IgG2b, kappa
Gene id: 3115
Gene name: HLA-DPB1
Gene alias: DPB1|HLA-DP1B
Gene description: major histocompatibility complex, class II, DP beta 1
Immunogen: Human non-T/non-B-cell-type acute lymphoblastic leukemia REH6 cell line.
Protein accession: P04440
Form: Liquid
Recommend dilutions: Flow Cytometry (0.5-1 ug/106 cells in 0.1 mL)
Immunofluorescence (0.5-1 ug/mL)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (0.5-1 ug/mL)
The optimal working dilution should be determined by the end user.
Storage buffer: In 10 mM PBS (0.05% BSA, 0.05% sodium azide).
Storage instruction: Store at 4°C.
Note: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Specificity: Recognizes a non-polymorphic determinant of DP-MHC class II. MHC class II antigens are transmembrane glycoproteins of non-covalently linked alpha (33-35 kDa) and beta (27-30 kDa) chains. It reportedly reacts with B- & non-T, non-B cell lines but not with T- and myeloid cell lines and leukemias. Differential expression of MHC class II antigens on fetal and adult lymphocytes, malignant B cells appears to reflect the stage of cell differentiation which may be useful in the study of lymphoproliferative disorders.
Size: 100 ug
Shipping condition: Blue Ice

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