Brand | Abnova |
Product type | Primary antibodies |
Reactivity | Human |
Clonality | Monoclonal |
Host species | Mouse |
Applications | IHC-P,IF,Flow Cyt |
Product description: | Mouse monoclonal antibody raised against native human HLA-A25/HLA-Aw32. |
Clone: | SPM417 |
Isotype: | IgG2a, kappa |
Gene id: | 3105|3106|3107 |
Gene name: | HLA-A |
Gene alias: | HLAA |
Gene description: | major histocompatibility complex, class I, A |
Immunogen: | Normal human peripheral blood lymphocytes of phenotype A1, Aw32, B7, B37, Cw-, Cw-, DR2, DRw10. |
Protein accession: | P01889;P30443;P30499 |
Form: | Liquid |
Recommend dilutions: | Flow Cytometry (0.5-1 ug/106 cells in 0.1 mL) Immunofluorescence (0.5-1 ug/mL) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (0.5-1 ug/mL) The optimal working dilution should be determined by the end user. |
Storage buffer: | In 10 mM PBS (0.05% BSA, 0.05% sodium azide). |
Storage instruction: | Store at 4°C. |
Note: | This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only. |
Specificity: | This monoclonal antibody reacts with cells bearing HLA-A25 or HLA-Aw32 antigens. In addition, a reaction was observed with a cell of phenotype A2, Aw31; B17, Bw49. HLA-A, with HLA-B and HLA-C, belongs to major histocompatibility complex (MHC) class I antigens and expresses constitutively on all nucleated cells. HLA system comprises closely linked genes controlling highly polymorphic proteins involved in the presentation of peptides to the T cell receptor, inhibition of NK cell cytotoxicity, and rejection of tissue allotransplantation. Specific alleles at HLA loci are associated with diseases. This antibody is specifically applicable for typing peripheral T cells for the antigens HLA-A25 and HLA-Aw32. |
Size: | 100 ug |
Shipping condition: | Blue Ice |