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Data sheet of HLA-A25/HLA-Aw32 monoclonal antibody, clone SPM417
| Brand | Abnova |
| Product type | Primary antibodies |
| Reactivity | Human |
| Clonality | Monoclonal |
| Host species | Mouse |
| Applications | IHC-P,IF,Flow Cyt |
More info about HLA-A25/HLA-Aw32 monoclonal antibody, clone SPM417
| Product description: | Mouse monoclonal antibody raised against native human HLA-A25/HLA-Aw32. |
| Clone: | SPM417 |
| Isotype: | IgG2a, kappa |
| Gene id: | 3105|3106|3107 |
| Gene name: | HLA-A |
| Gene alias: | HLAA |
| Gene description: | major histocompatibility complex, class I, A |
| Immunogen: | Normal human peripheral blood lymphocytes of phenotype A1, Aw32, B7, B37, Cw-, Cw-, DR2, DRw10. |
| Protein accession: | P01889;P30443;P30499 |
| Form: | Liquid |
| Recommend dilutions: | Flow Cytometry (0.5-1 ug/106 cells in 0.1 mL) Immunofluorescence (0.5-1 ug/mL) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (0.5-1 ug/mL) The optimal working dilution should be determined by the end user. |
| Storage buffer: | In 10 mM PBS (0.05% BSA, 0.05% sodium azide). |
| Storage instruction: | Store at 4°C. |
| Note: | This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only. |
| Specificity: | This monoclonal antibody reacts with cells bearing HLA-A25 or HLA-Aw32 antigens. In addition, a reaction was observed with a cell of phenotype A2, Aw31; B17, Bw49. HLA-A, with HLA-B and HLA-C, belongs to major histocompatibility complex (MHC) class I antigens and expresses constitutively on all nucleated cells. HLA system comprises closely linked genes controlling highly polymorphic proteins involved in the presentation of peptides to the T cell receptor, inhibition of NK cell cytotoxicity, and rejection of tissue allotransplantation. Specific alleles at HLA loci are associated with diseases. This antibody is specifically applicable for typing peripheral T cells for the antigens HLA-A25 and HLA-Aw32. |
| Size: | 100 ug |
| Shipping condition: | Blue Ice |