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Brand | Abnova |
Product type | Primary antibodies |
Reactivity | Mouse |
Host species | Rat |
Applications | Flow Cyt |
Brand: | Abnova |
Reference: | MAB12150 |
Product name: | Cd44 variant isoform 10-exon 16 (v10-e16) monoclonal antibody, clone RM1 |
Product description: | Rat monoclonal antibody raised against mouse Cd44 variant isoform 10-exon 16 (v10-e16). |
Clone: | RM1 |
Isotype: | IgG2a |
Gene id: | 12505 |
Gene name: | Cd44 |
Gene alias: | AU023126|AW121933|AW146109|HERMES|Ly-24|Pgp-1 |
Gene description: | CD44 antigen |
Immunogen: | Mouse Cd44 variant isoform 8-10 transfected cell. |
Form: | Liquid |
Recommend dilutions: | Flow cytomerty (1-10 ug/mL) Cancer stem cell enrichment The optimal working dilution should be determined by the end user. |
Storage buffer: | In PBS |
Storage instruction: | Store at 2-8°C. Aliquot to avoid repeated freezing and thawing. |
Note: | Cancer Stem Cell Enrichment Cancer Stem Cells (CSCs) have been identified as a subset of distinct population in many tumors and can drive cancer relapse and metastasis with their abilities to self-renew and differentiate into various types of cancer cells. Development of therapies specifically and effectively targeting CSCs thus is necessary to improve the survival and quality of life for cancer patients, especially for patients with metastatic diseases. Clone RM1 can be used for enrichment of CSCs with a cell sorter, and further be applied for studying mechanisms by which CSCs cause cancer relapse and metastasis to develop new drugs against CSCs. |
Product type: | Primary antibodies |
Host species: | Rat |
Antigen species / target species: | Mouse |
Reactivity: | Mouse |
Application image: | ![]() |
Application image note: | CSC enrichment from mouse cancer cell line using anti-CD44v10-e16 monoclonal antibody, clone RM1 (Cat # MAB12150) at 3 ug/mL. |
Applications: | Flow Cyt |
Shipping condition: | Blue Ice |