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Data sheet of HLA-G monoclonal antibody, clone 87G
| Brand | Abnova |
| Product type | Primary antibodies |
| Reactivity | Human |
| Host species | Mouse |
| Applications | ELISA,IHC-Fr,Func,Flow Cyt |
More info about HLA-G monoclonal antibody, clone 87G
| Brand: | Abnova |
| Reference: | MAB11223 |
| Product name: | HLA-G monoclonal antibody, clone 87G |
| Product description: | Mouse monoclonal antibody raised against HLA-G and B2M. |
| Clone: | 87G |
| Isotype: | IgG2a |
| Gene id: | 3135 |
| Gene name: | HLA-G |
| Gene alias: | MHC-G |
| Gene description: | major histocompatibility complex, class I, G |
| Immunogen: | HLA-B27 transgenic mice were imunized with H-2 identical murine cells transfected with and expressing genes encoding HLA-G and human beta2-microglobulin. |
| Form: | Liquid |
| Recommend dilutions: | ELISA (1 ug/mL) Flow Cytometry (2 ug/ml) Immunohistochemistry (Frozen sections) (10 ug/mL) The optimal working dilution should be determined by the end user. |
| Storage buffer: | In PBS, pH 7.4 |
| Storage instruction: | Store at 4°C. Do not freeze. Aliquot to avoid repeated freezing and thawing. |
| Product type: | Primary antibodies |
| Host species: | Mouse |
| Antigen species / target species: | Human |
| Specificity: | This antibody recognizes both membrane-bound and soluble forms of HLA-G (HLA-G1and HLA-G5). HLA-G belongs to the MHC Class I molecules (MHC Class Ib; nonclassical) and it is expressed on the surface of trophoblast cells. This antibody blocks interaction of HLA-G with inhibitory receptors. |
| Reactivity: | Human |
| Application image: |  |
| Application image note: | Analysis of cytolytical activity of human polyclonal NK cells on target melanoma cells. Blocking of HLA-G1 on transfectants with anti-human HLA-G (87G) restored specific lysis. Target cells : M8 cell line transfected with empty vector (column 1) and with HLA-G1 cDNA (columns 2-6). Blocking antibodies : Column 1-2 : none. Column 3 : Isotype mouse IgG2a control. Column 4 : HLA-G monoclonal antibody, clone 87G (Cat # MAB11223). Column 5 : HLA-G (Fab) monoclonal antibody, clone 87G. Column 6 : HLA-G monoclonal antibody, clone MEM-G/9 (Cat # MAB3855). |
| Applications: | ELISA,IHC-Fr,Func,Flow Cyt |
| Shipping condition: | Blue Ice |