Brand | Abnova |
Product type | Primary antibodies |
Reactivity | Human |
Host species | Mouse |
Applications | ELISA,WB-Ce |
Brand: | Abnova |
Reference: | MAB1108 |
Product name: | PTPRC monoclonal antibody, clone 3G4 |
Product description: | Mouse monoclonal antibody raised against partial recombinant PTPRC. |
Clone: | 3G4 |
Isotype: | IgG2a, kappa |
Gene id: | 5788 |
Gene name: | PTPRC |
Gene alias: | B220|CD45|CD45R|GP180|LCA|LY5|T200 |
Gene description: | protein tyrosine phosphatase, receptor type, C |
Genbank accession: | NM_002838 |
Immunogen: | Recombinant protein corresponding to amino acids 1029-1249 of human PTPRC. |
Protein accession: | NP_002829 |
Form: | Liquid |
Recommend dilutions: | Western Blot (1:1000-1:3000) The optimal working dilution should be determined by the end user. |
Storage buffer: | In PBS, pH 7.4 (0.09% sodium azide) |
Storage instruction: | Store at -20°C. Aliquot to avoid repeated freezing and thawing. |
Note: | This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only. |
Product type: | Primary antibodies |
Host species: | Mouse |
Antigen species / target species: | Human |
Reactivity: | Human |
Application image: | ![]() |
Application image note: | Western blot analysis of cell lysates of Jurkat (20 ug) were resolved by SDS - PAGE , transferred to NC membrane and probed with PTPRC monoclonal antibody , clone 3G4 (1 : 2000) (Cat # MAB1108). Proteins were visualized using a goat anti - mouse secondary antibody conjugated to HRP and an ECL detection system. |
Applications: | ELISA,WB-Ce |
Shipping condition: | Dry Ice |
Publications: | Epitope-specific crosslinking of CD45 down-regulates membrane-associated tyrosine phosphatase activity and triggers early signalling events in human activated T cells.Spertini F, Perret-Menoud V, Barbier N, Chatila T, Barbey C, Corthesy B. Immunology. 2004 Dec;113(4):441-52. |