Brand: | Abnova |
Reference: | H00120892-M01 |
Product name: | LRRK2 monoclonal antibody (M01), clone 3B2 |
Product description: | Mouse monoclonal antibody raised against a partial recombinant LRRK2. |
Clone: | 3B2 |
Isotype: | IgG1 Kappa |
Gene id: | 120892 |
Gene name: | LRRK2 |
Gene alias: | AURA17|DARDARIN|PARK8|RIPK7|ROCO2 |
Gene description: | leucine-rich repeat kinase 2 |
Genbank accession: | AY792511 |
Immunogen: | LRRK2 (AAV63975, 2161 a.a. ~ 2260 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
Immunogen sequence/protein sequence: | NSRNASIWLGCGHTDRGQLSFLDLNTEGYTSEEVADSRILCLALVHLPVEKESWIVSGTQSGTLLVINTEDGKKRHTLEKMTDSVTCLYCNSFSKQSKQK |
Protein accession: | AAV63975 |
Storage buffer: | In 1x PBS, pH 7.4 |
Storage instruction: | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
Quality control testing: | Antibody Reactive Against Recombinant Protein. |
Quality control testing picture: |  |
Quality control testing picture note: | Western Blot detection against Immunogen (36.63 KDa) . |
Product type: | Primary antibodies |
Host species: | Mouse |
Antigen species / target species: | Human |
Reactivity: | Human |
Application image: |  |
Application image note: | Detection limit for recombinant GST tagged LRRK2 is approximately 0.3ng/ml as a capture antibody. |
Applications: | S-ELISA,ELISA,WB-Re |
Shipping condition: | Dry Ice |
Publications: | LRRK2 regulates autophagic activity and localizes to specific membrane microdomains in a novel human genomic reporter cellular model.Alegre-Abarrategui J, Christian H, Lufino MM, Mutihac R, Venda LL, Ansorge O, Wade-Martins R. Hum Mol Genet. 2009 Nov 1;18(21):4022-34. Epub 2009 Jul 29. |