Brand | Abnova |
Reactivity | Human |
Applications | IHC,Flow Cyt |
Brand: | Abnova |
Reference: | RAB00096 |
Product name: | CLEC4M recombinant monoclonal antibody, clone 16E7 |
Product description: | Recombinant rabbit monoclonal antibody raised against human CLEC4M. |
Clone: | 16E7 |
Isotype: | IgG, kappa |
Gene id: | 10332 |
Gene name: | CLEC4M |
Gene alias: | CD209L|CD299|DC-SIGN2|DC-SIGNR|DCSIGNR|HP10347|L-SIGN|LSIGN|MGC129964|MGC47866 |
Gene description: | C-type lectin domain family 4, member M |
Immunogen: | Original antibody is raised against human CD299. |
Protein accession: | Q9H2X3 |
Form: | Liquid |
Recommend dilutions: | Flow Cytometry (1 ug/mL) Immunohistochemistry (5 ug/mL) The optimal working dilution should be determined by the end user. |
Storage buffer: | In PBS, pH 7.2 (0.02% Proclin 300). |
Storage instruction: | Store at 4°C. For long term storage store at -20°C. Aliquot to avoid repeated freezing and thawing. |
Antigen species / target species: | Human |
Specificity: | This antibody recognizes human CLEC4M, which is an oligomeric type II transmembrane protein with a C-type lectin extracellular domain, the expression of which is restricted to immature DC, macrophages in the lung, and endothelial cells in the liver. It binds ICAM-3 and ICAM-7 to mediate the interaction of DC with T lymphocytes and endothelial cells in the initial stages of immune response and in the migratory behavior of DC. CD299 also binds the gp120 protein of HIV and the E2 envelope protein of HCV, thereby playing a role in viral infection. |
Reactivity: | Human |
Applications: | IHC,Flow Cyt |
Shipping condition: | Dry Ice |