Brand | Abnova |
Product type | Primary antibodies |
Reactivity | Human |
Host species | Rabbit |
Applications | WB-Ce,IHC-P |
Brand: | Abnova |
Reference: | PAB3831 |
Product name: | BMPR1A polyclonal antibody |
Product description: | Rabbit polyclonal antibody raised against synthetic peptide of BMPR1A. |
Gene id: | 657 |
Gene name: | BMPR1A |
Gene alias: | 10q23del|ACVRLK3|ALK3|CD292 |
Gene description: | bone morphogenetic protein receptor, type IA |
Immunogen: | A synthetic peptide (conjugated with KLH) corresponding to amino acids 39-69 at N-terminus of human BMPR1A. |
Protein accession: | NP_004320 |
Form: | Liquid |
Recommend dilutions: | Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:50-100) Western Blot (1:1000) The optimal working dilution should be determined by the end user. |
Storage buffer: | In PBS (0.09% sodium azide) |
Storage instruction: | Store at 4°C. For long term storage store at -20°C. Aliquot to avoid repeated freezing and thawing. |
Note: | This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only. |
Product type: | Primary antibodies |
Host species: | Rabbit |
Antigen species / target species: | Human |
Reactivity: | Human |
Application image: | ![]() |
Application image note: | Formalin-fixed and paraffin-embedded human cancer tissue reacted with BMPR1A polyclonal antibody (Cat # PAB3831) , which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma |
Applications: | WB-Ce,IHC-P |
Shipping condition: | Dry Ice |
Publications: | Germline mutations in BMPR1A/ALK3 cause a subset of cases of juvenile polyposis syndrome and of Cowden and Bannayan-Riley-Ruvalcaba syndromes.Zhou XP, Woodford-Richens K, Lehtonen R, Kurose K, Aldred M, Hampel H, Launonen V, Virta S, Pilarski R, Salovaara R, Bodmer WF, Conrad BA, Dunlop M, Hodgson SV, Iwama T, Jarvinen H, Kellokumpu I, Kim JC, Leggett B, Markie D, Mecklin JP, Neale K, Phillips R, Piris J, Rozen P, Houlston RS, Aaltonen LA, Tomlinson IP, Eng C. Am J Hum Genet. 2001 Oct;69(4):704-11. Epub 2001 Aug 30. |