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Data sheet of SMURF2 polyclonal antibody
| Brand | Abnova |
| Product type | Primary antibodies |
| Reactivity | Human,Mouse |
| Host species | Rabbit |
| Applications | WB-Ti,IHC-P |
More info about SMURF2 polyclonal antibody
| Brand: | Abnova |
| Reference: | PAB1749 |
| Product name: | SMURF2 polyclonal antibody |
| Product description: | Rabbit polyclonal antibody raised against synthetic peptide of SMURF2. |
| Gene id: | 64750 |
| Gene name: | SMURF2 |
| Gene alias: | DKFZp686F0270|MGC138150 |
| Gene description: | SMAD specific E3 ubiquitin protein ligase 2 |
| Immunogen: | A synthetic peptide (conjugated with KLH) corresponding to N-terminus of human SMURF2. |
| Protein accession: | SUF2_HUMAN |
| Form: | Liquid |
| Recommend dilutions: | Western Blot (1:1000) Immunohistochemistry (1:50-100) The optimal working dilution should be determined by the end user. |
| Storage buffer: | In PBS (0.09% sodium azide) |
| Storage instruction: | Store at 4°C. For long term storage store at -20°C. Aliquot to avoid repeated freezing and thawing. |
| Note: | This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only. |
| Product type: | Primary antibodies |
| Host species: | Rabbit |
| Antigen species / target species: | Human |
| Reactivity: | Human,Mouse |
| Application image: |  |
| Application image note: | Formalin-fixed and paraffin-embedded human cancer tissue reacted with SMURF2 polyclonal antibody (Cat # PAB1749) , which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma. |
| Applications: | WB-Ti,IHC-P |
| Shipping condition: | Dry Ice |
| Publications: | Smurf2 is a ubiquitin E3 ligase mediating proteasome-dependent degradation of Smad2 in transforming growth factor-beta signaling.Lin X, Liang M, Feng XH. J Biol Chem. 2000 Nov 24;275(47):36818-22. |