Brand | Abnova |
Product type | Primary antibodies |
Reactivity | Human |
Host species | Rabbit |
Applications | WB-Ce,IHC-P |
Brand: | Abnova |
Reference: | PAB1737 |
Product name: | NEDD8 polyclonal antibody |
Product description: | Rabbit polyclonal antibody raised against synthetic peptide of NEDD8. |
Gene id: | 4738 |
Gene name: | NEDD8 |
Gene alias: | FLJ43224|MGC104393|MGC125896|MGC125897|Nedd-8 |
Gene description: | neural precursor cell expressed, developmentally down-regulated 8 |
Immunogen: | A synthetic peptide (conjugated with KLH) corresponding to N-terminus of human NEDD8. |
Protein accession: | NP_006147;Q15843 |
Form: | Liquid |
Recommend dilutions: | Western Blot (1:1000) Immunohistochemistry (1:50-100) The optimal working dilution should be determined by the end user. |
Storage buffer: | In PBS (0.09% sodium azide) |
Storage instruction: | Store at 4°C. For long term storage store at -20°C. Aliquot to avoid repeated freezing and thawing. |
Note: | This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only. |
Product type: | Primary antibodies |
Host species: | Rabbit |
Antigen species / target species: | Human |
Reactivity: | Human |
Application image: | ![]() |
Application image note: | Western blot analysis of NEDD8 polyclonal antibody (Cat # PAB1737) in HeLa cell lysate. NEDD8 (arrow) was detected using purified polyclonal antibody. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence. |
Applications: | WB-Ce,IHC-P |
Shipping condition: | Dry Ice |
Publications: | The NEDD8 pathway is required for proteasome-mediated degradation of human estrogen receptor (ER)-alpha and essential for the antiproliferative activity of ICI 182,780 in ERalpha-positive breast cancer cells.Fan M, Bigsby RM, Nephew KP. Mol Endocrinol. 2003 Mar;17(3):356-65. Epub 2002 Dec 18. |