Cart 0 Product Products (empty)
No products
To be determined Shipping
0,00 € Total
Prices are tax excluded
Product successfully added to your shopping cart
Quantity
Total
There are 0 items in your cart. There is 1 item in your cart.
Total products (tax excl.)
Total shipping (tax excl.) To be determined
Total (tax excl.)
Data sheet of COL1A1 polyclonal antibody
| Brand | Abnova |
| Product type | Primary antibodies |
| Reactivity | Birds,Fish,Human,Mammals,Mouse,Rat |
| Host species | Rabbit |
| Applications | IHC,WB-Ti,IF |
More info about COL1A1 polyclonal antibody
| Brand: | Abnova |
| Reference: | PAB17204 |
| Product name: | COL1A1 polyclonal antibody |
| Product description: | Rabbit polyclonal antibody raised against synthetic peptide of COL1A1. |
| Gene id: | 1277 |
| Gene name: | COL1A1 |
| Gene alias: | OI4 |
| Gene description: | collagen, type I, alpha 1 |
| Immunogen: | A synthetic peptide corresponding to human COL1A1. |
| Protein accession: | P02452 |
| Form: | Liquid |
| Recommend dilutions: | Western Blot (1:1000) Immunohistochemistry (1:100) The optimal working dilution should be determined by the end user. |
| Storage buffer: | In 10 mM HEPES, 150 mM NaCl, pH 7.5 (50% glycerol, 0.1 mg/mL BSA) |
| Storage instruction: | Store at -20°C. Aliquot to avoid repeated freezing and thawing. |
| Product type: | Primary antibodies |
| Host species: | Rabbit |
| Antigen species / target species: | Human |
| Specificity: | This antibody has been directly tested for reactivity in human, mouse and rat. Based on the homology of the antigen this antibody is expected to recognize the collagen I 1 polypeptide in most, if not all, species of mammals, birds, amphibians, and fishes. specific to the propeptide portion of the ~180 KDa collagen I alpha1 polypeptide in human lung fibroblast extract. This antibody also works well for immunohistochemistry on paraformaldehyde-fixed sections with a simple antigen-retrieval protocol (incubate slides for 20 minutes at 90°C in 10 mM sodium citrate (pH 6.0)/ 0.1% Tween-20). Note that in paraffin sections of formaldehyde-fixed fibrotic mouse lung tissue, This antibody recognizes collagen I molecules that are still associated with the cells in which they were synthesized. |
| Reactivity: | Birds,Fish,Human,Mammals,Mouse,Rat |
| Application image: |  |
| Application image note: | Immunofluorescence staining of fibrotic mouse lung tissue showing specific staining of COL1A1 molecules (red) that are still associated with the cells in which they were synthesized. Using COL1A1 polyclonal antibody (Cat # PAB17204). |
| Applications: | IHC,WB-Ti,IF |
| Shipping condition: | Dry Ice |
| Publications: | Mutations near amino end of alpha1(I) collagen cause combined osteogenesis imperfecta/Ehlers-Danlos syndrome by interference with N-propeptide processing.Cabral WA, Makareeva E, Colige A, Letocha AD, Ty JM, Yeowell HN, Pals G, Leikin S, Marini JC. J Biol Chem. 2005 May 13;280(19):19259-69. Epub 2005 Feb 22. |