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Data sheet of CHEK2 (phospho T387) polyclonal antibody
| Brand | Abnova |
| Product type | Primary antibodies |
| Reactivity | Human,Mouse,Rat |
| Host species | Rabbit |
| Applications | ELISA,WB-Ce,IHC-P |
More info about CHEK2 (phospho T387) polyclonal antibody
| Brand: | Abnova |
| Reference: | PAB16966 |
| Product name: | CHEK2 (phospho T387) polyclonal antibody |
| Product description: | Rabbit polyclonal antibody raised against synthetic phosphopeptide of CHEK2. |
| Gene id: | 11200 |
| Gene name: | CHEK2 |
| Gene alias: | CDS1|CHK2|HuCds1|LFS2|PP1425|RAD53 |
| Gene description: | CHK2 checkpoint homolog (S. pombe) |
| Immunogen: | Synthetic phosphopeptide corresponding to residues surrounding T387 of human CHEK2. |
| Protein accession: | O96017 |
| Form: | Liquid |
| Recommend dilutions: | Western Blot (1:500-1:1000) Immunohistochemistry (1:50-1:100) ELISA (1:4000) The optimal working dilution should be determined by the end user. |
| Storage buffer: | In 20 mM PBS, 0.15 M NaCl, pH 7.2 (0.01% sodium azide) |
| Storage instruction: | Store at 4°C for three months. For long term storage store at -20°C. Aliquot to avoid repeated freezing and thawing. |
| Note: | This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only. |
| Product type: | Primary antibodies |
| Host species: | Rabbit |
| Antigen species / target species: | Human |
| Specificity: | This antibody detects endogenous levels of CHEK2 only when phosphorylated at serine 317. |
| Reactivity: | Human,Mouse,Rat |
| Application image: |  |
| Application image note: | Immunohistochemical analysis of paraffin-embedded human lung adenocarcinoma tissue using CHEK2 (phospho Thr387) polyclonal antibody (Cat # PAB16966). |
| Applications: | ELISA,WB-Ce,IHC-P |
| Shipping condition: | Dry Ice |
| Publications: | The Wip1 phosphatase (PPM1D) antagonizes activation of the Chk2 tumour suppressor kinase.Oliva-Trastoy M, Berthonaud V, Chevalier A, Ducrot C, Marsolier-Kergoat MC, Mann C, Leteurtre F. Oncogene. 2007 Mar 1;26(10):1449-58. Epub 2006 Aug 28. |