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Data sheet of BIRC7 polyclonal antibody
| Brand | Abnova |
| Product type | Primary antibodies |
| Reactivity | Human,Mouse,Rat |
| Host species | Rabbit |
| Applications | IP,IHC-Fr,IHC-P,WB-Re |
More info about BIRC7 polyclonal antibody
| Brand: | Abnova |
| Reference: | PAB14670 |
| Product name: | BIRC7 polyclonal antibody |
| Product description: | Rabbit polyclonal antibody raised against synthetic peptide of BIRC7. |
| Gene id: | 79444 |
| Gene name: | BIRC7 |
| Gene alias: | KIAP|LIVIN|ML-IAP|MLIAP|RNF50 |
| Gene description: | baculoviral IAP repeat-containing 7 |
| Immunogen: | A synthetic peptide corresponding to amino acids 199-217 of human BIRC7. |
| Immunogen sequence/protein sequence: | PELPTPRREVQSESAQEPG |
| Protein accession: | NP_647478;NP_071444.1 |
| Form: | Liquid |
| Recommend dilutions: | Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:1000-1:5000) Immunoprecipitation (1:50-1:200) Western Blot (1:1000-1:2000) The optimal working dilution should be determined by the end user. |
| Storage buffer: | In serum (0.05% sodium azide) |
| Storage instruction: | Store at -20°C. Aliquot to avoid repeated freezing and thawing. |
| Note: | This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only. |
| Product type: | Primary antibodies |
| Host species: | Rabbit |
| Antigen species / target species: | Human |
| Specificity: | Livin is a short-lived protein that is thought to be degraded by the ubiquitin-proteasome pathway. Thus users may want to do a time course when examining the effects of treatments on Livin expression. Users are encouraged to refer to the literature for additional information; for example, Ma et al. 2006. Livin has been shown to undergo proteolytic cleavage during apoptosis. Thus the molecular weight of Livin observed on Western blots may vary depending on the presence of absence of cleavage fragments. |
| Reactivity: | Human,Mouse,Rat |
| Application image: |  |
| Application image note: | Immunohistochemical analysis of BIRC7 in formalin-fixed, paraffin embedded human tonsil (secondary nodule) using BIRC7 polyclonal antibody (Cat #PAB14670) at 1 : 2000. Hematoxylin-eosin counterstain. |
| Applications: | IP,IHC-Fr,IHC-P,WB-Re |
| Shipping condition: | Dry Ice |
| Publications: | Caspase-mediated cleavage converts Livin from an antiapoptotic to a proapoptotic factor: implications for drug-resistant melanoma.Nachmias B, Ashhab Y, Bucholtz V, Drize O, Kadouri L, Lotem M, Peretz T, Mandelboim O, Ben-Yehuda D. Cancer Res. 2003 Oct 1;63(19):6340-9. |