Brand | Abnova |
Product type | Primary antibodies |
Reactivity | Bovine,Chicken,Dog,Human,Mouse,Rat,Zebra fish |
Host species | Rabbit |
Applications | WB-Ti |
Brand: | Abnova |
Reference: | PAB14527 |
Product name: | Tph1 (phospho S260) polyclonal antibody |
Product description: | Rabbit polyclonal antibody raised against synthetic phosphopeptide of Tph1. |
Gene id: | 24848 |
Gene name: | Tph1 |
Gene alias: | Tph |
Gene description: | tryptophan hydroxylase 1 |
Immunogen: | Synthetic phosphopeptide corresponding to residues surrounding S260 of rat Tph1. |
Protein accession: | P09810 |
Form: | Liquid |
Recommend dilutions: | Western Blot (1:1000) The optimal working dilution should be determined by the end user. |
Storage buffer: | In 10 mM HEPES, 150 mM NaCl, pH 7.5 (50% glycerol, 10% BSA) |
Storage instruction: | Store at -20°C. Aliquot to avoid repeated freezing and thawing. |
Product type: | Primary antibodies |
Host species: | Rabbit |
Antigen species / target species: | Rat |
Specificity: | Specific for the ~55 KDa tryptophan hydroxylase protein phosphorylated at Ser260. It is anticipated that This antibody will react with bovine, canine, chicken, mouse and zebra fish based on the fact that these species have 100% homology with the amino acid sequence used as antigen. |
Reactivity: | Bovine,Chicken,Dog,Human,Mouse,Rat,Zebra fish |
Application image: | ![]() |
Application image note: | Western blot of rat brainstem lysate showing specific immunolabeling of the ~55k Tph1 protein phosphorylated at Ser260. The labeling is specifically blocked by the phosphopeptide (Phos-pep, lane 1) used as antigen. The corresponding non-phosphopeptide (Nonphos-pep, lane 2) did not block the immunolabeling. |
Applications: | WB-Ti |
Shipping condition: | Dry Ice |
Publications: | Identification of substrate orienting and phosphorylation sites within tryptophan hydroxylase using homology-based molecular modeling.Jiang GC, Yohrling GJ 4th, Schmitt JD, Vrana KE. J Mol Biol. 2000 Sep 29;302(4):1005-17. |