Brand: | Abnova |
Reference: | PAB12440 |
Product name: | EGLN1 polyclonal antibody |
Product description: | Rabbit polyclonal antibody raised against synthetic peptide of EGLN1. |
Gene id: | 54583 |
Gene name: | EGLN1 |
Gene alias: | C1orf12|DKFZp761F179|ECYT3|HIFPH2|HPH2|PHD2|SM-20|SM20|ZMYND6 |
Gene description: | egl nine homolog 1 (C. elegans) |
Immunogen: | A synthetic peptide corresponding to amino acids 350-426 of human EGLN1. |
Protein accession: | Q9GZT9 |
Form: | Liquid |
Recommend dilutions: | The optimal working dilution should be determined by the end user. |
Storage buffer: | In Tris-citrate/phosphate buffer, pH 7.0-8.0 (0.09% sodium azide) |
Storage instruction: | Store at 4°C. Do not freeze. |
Note: | This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only. |
Product type: | Primary antibodies |
Host species: | Rabbit |
Antigen species / target species: | Human |
Specificity: | This antibody is specific to human HIF prolyl hydroxylase 2. There is 83% homology between the immunogen used for this antibody and the rat and mouse proteins. |
Reactivity: | Human |
Application image: |  |
Application image note: | Western blot analysis of EGLN1 using EGLN1 polyclonal antibody (Cat # PAB12440). Samples : Recombinant FLAG-His-EGLN2, EGLN1 and EGLN3 (10 ng/lane), HeLa whole cell lysate and MEF. |
Applications: | WB,IP,IHC |
Shipping condition: | Blue Ice |
Publications: | The new tumor-suppressor gene inhibitor of growth family member 4 (ING4) regulates the production of proangiogenic molecules by myeloma cells and suppresses hypoxia-inducible factor-1 alpha (HIF-1alpha) activity: involvement in myeloma-induced angiogenesis.Colla S, Tagliaferri S, Morandi F, Lunghi P, Donofrio G, Martorana D, Mancini C, Lazzaretti M, Mazzera L, Ravanetti L, Bonomini S, Ferrari L, Miranda C, Ladetto M, Neri TM, Neri A, Greco A, Mangoni M, Bonati A, Rizzoli V, Giuliani N. Blood. 2007 Dec 15;110(13):4464-75. Epub 2007 Sep 11. |