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Data sheet of MDM2 polyclonal antibody
| Brand | Abnova |
| Product type | Primary antibodies |
| Reactivity | Human,Mouse,Rat |
| Host species | Rabbit |
| Applications | IHC-P,IF |
More info about MDM2 polyclonal antibody
| Brand: | Abnova |
| Reference: | PAB12253 |
| Product name: | MDM2 polyclonal antibody |
| Product description: | Rabbit polyclonal antibody raised against synthetic peptide of MDM2. |
| Gene id: | 4193 |
| Gene name: | MDM2 |
| Gene alias: | HDMX|MGC71221|hdm2 |
| Gene description: | Mdm2 p53 binding protein homolog (mouse) |
| Immunogen: | A synthetic peptide (conjugated with KLH) corresponding to residues surrounding S166 of human MDM2. |
| Immunogen sequence/protein sequence: | AISET |
| Protein accession: | Q00987 |
| Form: | Liquid |
| Concentration: | 1 mg/mL |
| Recommend dilutions: | Immunohistochemistry (1:50-1:100) Immunofluorescence (1:100-1:200) The optimal working dilution should be determined by the end user. |
| Storage buffer: | In PBS (without Mg2+ and Ca2+), 150 mM NaCl, pH 7.4 (50% glycerol, 0.02% sodium azide) |
| Storage instruction: | Store at -20°C. Aliquot to avoid repeated freezing and thawing. |
| Quality control testing: | Antibody Reactive Against Synthetic Peptide. |
| Note: | This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only. |
| Product type: | Primary antibodies |
| Host species: | Rabbit |
| Antigen species / target species: | Human |
| Specificity: | MDM2 (Ab-166) Antibody detects endogenous levels of total MDM2 protein. |
| Reactivity: | Human,Mouse,Rat |
| Application image: |  |
| Application image note: | Immunofluorescence staining of methanol-fixed HeLa cells using MDM2 polyclonal antibody (Cat # PAB12253, Red). |
| Applications: | IHC-P,IF |
| Shipping condition: | Dry Ice |
| Publications: | p300/MDM2 complexes participate in MDM2-mediated p53 degradation.Grossman SR, Perez M, Kung AL, Joseph M, Mansur C, Xiao ZX, Kumar S, Howley PM, Livingston DM. Mol Cell. 1998 Oct;2(4):405-15. |