CTLA4 monoclonal antibody, clone ANC152.2/8H5 View larger

CTLA4 monoclonal antibody, clone ANC152.2/8H5

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Data sheet of CTLA4 monoclonal antibody, clone ANC152.2/8H5

BrandAbnova
Product typePrimary antibodies
ReactivityHuman
Host speciesMouse
ApplicationsEIA,Flow Cyt

More info about CTLA4 monoclonal antibody, clone ANC152.2/8H5

Brand: Abnova
Reference: MAB6927
Product name: CTLA4 monoclonal antibody, clone ANC152.2/8H5
Product description: Mouse monoclonal antibody raised against CTLA4.
Clone: ANC152.2/8H5
Isotype: IgG1, kappa
Gene id: 1493
Gene name: CTLA4
Gene alias: CD152|CELIAC3|CTLA-4|GSE|IDDM12
Gene description: cytotoxic T-lymphocyte-associated protein 4
Immunogen: A mixture of stimulated human PBL's and human CTLA4 Ig fusion protein.
Form: Liquid
Recommend dilutions: The optimal working dilution should be determined by the end user.
Storage buffer: In 50 mM sodium phosphate buffer, 100 mM potassium Chloride, 150 mM NaCl, pH 7.5 (0.5 mg/mL gentamicin sulfate)
Storage instruction: Store at 4°C.
Product type: Primary antibodies
Host species: Mouse
Antigen species / target species: Human
Specificity: MAB6927 blocks binding of CD152 (CTLA-4) Ig fusion protein to its CD80/CD86 receptor, and has been reported to modulate suppressive function of human T Regulatory cells in Vitro. It can bind to intracellular CD152 in fixed permeabolized cells. The F(ab')2 form has been used to inhibit proliferation of activated T cells in vitro in a cholera toxin model.
Reactivity: Human
Application image: MAB6927-84-87-1.jpg
Application image note: CTLA4 monoclonal antibody, clone ANC152.2/8H5 (Cat # MAB6927) blocked the binding of recombinant CTLA4-muIg fusion protein/R-PE conjugate to CD80 and CD86 expressed on human Raji cells.
Applications: EIA,Flow Cyt
Shipping condition: Blue Ice
Publications: Activated self-MHC-reactive T cells have the cytokine phenotype of Th3/T regulatory cell 1 T cells.Kitani A, Chua K, Nakamura K, Strober W.
J Immunol. 2000 Jul 15;165(2):691-702.

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