Brand: | Abnova |
Reference: | MAB6896 |
Product name: | CD4 monoclonal antibody, clone QS4120 |
Product description: | Mouse monoclonal antibody raised against CD4. |
Clone: | QS4120 |
Isotype: | IgG1 |
Gene id: | 920 |
Gene name: | CD4 |
Gene alias: | CD4mut |
Gene description: | CD4 molecule |
Immunogen: | CD4+ transfectant/ CEM. |
Form: | Liquid |
Recommend dilutions: | The optimal working dilution should be determined by the end user. |
Storage buffer: | In 50 mM sodium phosphate buffer, 100 mM potassium Chloride, 150 mM NaCl, pH 7.5 (0.5 mg/mL gentamicin sulfate) |
Storage instruction: | Store at 4°C. |
Product type: | Primary antibodies |
Host species: | Mouse |
Antigen species / target species: | Human |
Specificity: | Antibody QS4120 recognizes an epitope in the CDR2-like loop within domain 1 region of the CD4 molecule. Antibody QS4120 will block binding of HIV-1 gp120 protein to CD4 and also blocks HLA Class II Rosette formation. |
Reactivity: | Human |
Applications: | IP,IHC-Fr,Flow Cyt |
Shipping condition: | Blue Ice |
Publications: | A specific CD4 epitope bound by tregalizumab mediates activation of regulatory T cells by a unique signaling pathway.Helling B, Konig M, Dalken B, Engling A, Kromer W, Heim K, Wallmeier H, Haas J, Wildemann B, Fritz B, Jonuleit H, Kubach J, Dingermann T, Radeke HH, Osterroth F, Uherek C, Czeloth N, Schuttrumpf J Immunol Cell Biol. 2014 Dec 16. doi: 10.1038/icb.2014.102. |