Brand | Abnova |
Product type | Primary antibodies |
Reactivity | Human,Mouse,Rat |
Host species | Mouse |
Applications | WB-Ce,WB-Ti,IHC-P |
Brand: | Abnova |
Reference: | MAB6243 |
Product name: | CASP7 monoclonal antibody, clone 25B881.1 |
Product description: | Mouse monoclonal antibody raised against recombinant CASP7. |
Clone: | 25B881.1 |
Isotype: | IgG1 |
Gene id: | 840 |
Gene name: | CASP7 |
Gene alias: | CMH-1|ICE-LAP3|MCH3 |
Gene description: | caspase 7, apoptosis-related cysteine peptidase |
Immunogen: | Recombinant protein corresponding to human CASP7. |
Protein accession: | NP_001081408 |
Form: | Liquid |
Recommend dilutions: | Western Blot (1-2 ug/mL) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (5 ug/mL) The optimal working dilution should be determined by the end user. |
Storage buffer: | In PBS (0.05% sodium azide) |
Storage instruction: | Store at 4°C. For long term storage store at -20°C. Aliquot to avoid repeated freezing and thawing. |
Note: | This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only. |
Product type: | Primary antibodies |
Host species: | Mouse |
Antigen species / target species: | Human |
Reactivity: | Human,Mouse,Rat |
Application image: | ![]() |
Application image note: | Western blot analysis of CASP7 in Jurkat cells using CASP7 monoclonal antibody, clone 25B881.1 (Cat #MAB6243) at 1 ug/mL. Cells were treated with 2 uM staurosporine for different time periods. CASP7 activation is detected in western blots by the presence of CASP7 cleavage fragments. The antibody detected both pro (full-length) and active (cleaved) CASP7, depending on the treatment time points. A basal level of endogenous intermediate CASP7 can be see in untreated Jurkat cells. |
Applications: | WB-Ce,WB-Ti,IHC-P |
Shipping condition: | Dry Ice |
Publications: | Mch3, a novel human apoptotic cysteine protease highly related to CPP32.Fernandes-Alnemri T, Takahashi A, Armstrong R, Krebs J, Fritz L, Tomaselli KJ, Wang L, Yu Z, Croce CM, Salveson G, et al.. Cancer Res. 1995 Dec 15;55(24):6045-52. |