CASP7 monoclonal antibody, clone 25B881.1 View larger

CASP7 monoclonal antibody, clone 25B881.1

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Data sheet of CASP7 monoclonal antibody, clone 25B881.1

BrandAbnova
Product typePrimary antibodies
ReactivityHuman,Mouse,Rat
Host speciesMouse
ApplicationsWB-Ce,WB-Ti,IHC-P

More info about CASP7 monoclonal antibody, clone 25B881.1

Brand: Abnova
Reference: MAB6243
Product name: CASP7 monoclonal antibody, clone 25B881.1
Product description: Mouse monoclonal antibody raised against recombinant CASP7.
Clone: 25B881.1
Isotype: IgG1
Gene id: 840
Gene name: CASP7
Gene alias: CMH-1|ICE-LAP3|MCH3
Gene description: caspase 7, apoptosis-related cysteine peptidase
Immunogen: Recombinant protein corresponding to human CASP7.
Protein accession: NP_001081408
Form: Liquid
Recommend dilutions: Western Blot (1-2 ug/mL)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (5 ug/mL)
The optimal working dilution should be determined by the end user.
Storage buffer: In PBS (0.05% sodium azide)
Storage instruction: Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Note: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Product type: Primary antibodies
Host species: Mouse
Antigen species / target species: Human
Reactivity: Human,Mouse,Rat
Application image: MAB6243-46-6-1.jpg
Application image note: Western blot analysis of CASP7 in Jurkat cells using CASP7 monoclonal antibody, clone 25B881.1 (Cat #MAB6243) at 1 ug/mL. Cells were treated with 2 uM staurosporine for different time periods. CASP7 activation is detected in western blots by the presence of CASP7 cleavage fragments. The antibody detected both pro (full-length) and active (cleaved) CASP7, depending on the treatment time points. A basal level of endogenous intermediate CASP7 can be see in untreated Jurkat cells.
Applications: WB-Ce,WB-Ti,IHC-P
Shipping condition: Dry Ice
Publications: Mch3, a novel human apoptotic cysteine protease highly related to CPP32.Fernandes-Alnemri T, Takahashi A, Armstrong R, Krebs J, Fritz L, Tomaselli KJ, Wang L, Yu Z, Croce CM, Salveson G, et al..
Cancer Res. 1995 Dec 15;55(24):6045-52.

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