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Data sheet of CD14 monoclonal antibody, clone biG 4
| Brand | Abnova |
| Product type | Primary antibodies |
| Reactivity | Human |
| Host species | Mouse |
| Applications | ELISA |
More info about CD14 monoclonal antibody, clone biG 4
| Brand: | Abnova |
| Reference: | MAB5657 |
| Product name: | CD14 monoclonal antibody, clone biG 4 |
| Product description: | Mouse monoclonal antibody raised against CD14. |
| Clone: | biG 4 |
| Isotype: | IgG1 |
| Gene id: | 929 |
| Gene name: | CD14 |
| Gene alias: | - |
| Gene description: | CD14 molecule |
| Immunogen: | Monocytes of human and different animals as well as soluble human CD14. |
| Form: | Lyophilized |
| Recommend dilutions: | The optimal working dilution should be determined by the end user. |
| Storage buffer: | Lyophilized from PBS |
| Storage instruction: | Store at -20°C on dry atmosphere. After reconstitution with deionized water, store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| Product type: | Primary antibodies |
| Host species: | Mouse |
| Antigen species / target species: | Human |
| Specificity: | biG 4 represents an excellent marker for CD14. CD14 has been shown to be involved in the LPS-induced cell activation. This antigen is present as a membrane bound form and as soluble antigen, both involved in cell stimulation by LPS. The plasma protein LBP plays an important role in this LPS-CD14 mediated cell activation. Monocytes and PMN are activated by the LBP-LPS complex via membrane CD14. The CD14 glycoprotein, gp 55, is present on most monocytic and macrophages like cell types: monocytes, macrophages, Kupffer cells, pleural phagocytic cells and dendritic reticular cells. CD14 is also observed on granulocytes and activated or transformed B-cells. Furthermore CD14 is present in a soluble form in human serum, urine and other body fluids. The CD14 molecule has been reported to be a receptor for Endotoxin. |
| Reactivity: | Human |
| Applications: | ELISA |
| Shipping condition: | Dry Ice |
| Publications: | LPS-binding protein and CD14-dependent attachment of hepatitis B surface antigen to monocytes is determined by the phospholipid moiety of the particles.Vanlandschoot P, Van Houtte F, Roobrouck A, Farhoudi A, Stelter F, Peterson DL, Gomez-Gutierrez J, Gavilanes F, Leroux-Roels G. J Gen Virol. 2002 Sep;83(Pt 9):2279-89. |