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Data sheet of ITGA2B monoclonal antibody, clone SZ.22 (FITC)
| Brand | Abnova |
| Product type | Primary antibodies |
| Reactivity | Human |
| Host species | Mouse |
| Applications | WB,IHC-Fr,ICC,Flow Cyt |
More info about ITGA2B monoclonal antibody, clone SZ.22 (FITC)
| Brand: | Abnova |
| Reference: | MAB5497 |
| Product name: | ITGA2B monoclonal antibody, clone SZ.22 (FITC) |
| Product description: | Mouse monoclonal antibody raised against native ITGA2B. |
| Clone: | SZ.22 |
| Isotype: | IgG1 |
| Gene id: | 3674 |
| Gene name: | ITGA2B |
| Gene alias: | CD41|CD41B|GP2B|GPIIb|GTA|HPA3 |
| Gene description: | integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) |
| Immunogen: | Native purified ITGA2B from human washed platelets. |
| Form: | Liquid |
| Recommend dilutions: | Immunohistochemistry (Frozen sections) (1:50-1:100) Immunocytochemistry (1:50-1:100) Immunofluorescence (20ul/106 platelets/test) Flow Cytometry (20ul/106 platelets/test) The optimal working dilution should be determined |
| Storage buffer: | In PBS (2 mg/mL BSA, 0.09% sodium azide) |
| Storage instruction: | Store in the dark at 4°C. Do not freeze. Avoid prolonged exposure to light. Aliquot to avoid repeated freezing and thawing. |
| Note: | This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only. |
| Conjugate tag: | FITC |
| Product type: | Primary antibodies |
| Host species: | Mouse |
| Antigen species / target species: | Human |
| Specificity: | The CD41 antigen (platelet GPIIb; alpha IIb integrin) is a glycoprotein composed of 2 chains, GPIIb alpha (120 KDa) and GPIIb beta (23KDa), linked by one disulfide bond. CD41 is always non-covalently associated with CD61 (platelet GPIIIa, beta 3 integrin), to form the GPIIb-IIIa (CD41/CD61) complex. CD41 is expressed by platelets, megakaryocytes and by a small subset of CD34+ cells suggesting that CD41/CD61 is the earliest marker of the megakaryocytic lineage. Clone SZ.22 reacts with the alpha chain of CD41. It has been assigned to the CD41 cluster of differentiation at the 5th International Workshop on human Leucocyte Differentiation Antigens in Boston, in 1993. |
| Reactivity: | Human |
| Applications: | WB,IHC-Fr,ICC,Flow Cyt |
| Shipping condition: | Blue Ice |
| Publications: | The value of flow cytometric analysis of platelet glycoprotein expression of CD34+ cells measured under conditions that prevent P-selectin-mediated binding of platelets.Dercksen MW, Weimar IS, Richel DJ, Breton-Gorius J, Vainchenker W, Slaper-Cortenbach CM, Pinedo HM, von dem Borne AE, Gerritsen WR, van der Schoot CE. Blood. 1995 Nov 15;86(10):3771-82. |