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Data sheet of EGFR monoclonal antibody, clone EGFR1 (Biotin)
| Brand | Abnova |
| Product type | Primary antibodies |
| Reactivity | Human |
| Host species | Mouse |
| Applications | IHC,Flow Cyt |
More info about EGFR monoclonal antibody, clone EGFR1 (Biotin)
| Brand: | Abnova |
| Reference: | MAB5444 |
| Product name: | EGFR monoclonal antibody, clone EGFR1 (Biotin) |
| Product description: | Mouse monoclonal antibody raised against native EGFR. |
| Clone: | EGFR1 |
| Isotype: | IgG2b |
| Gene id: | 1956 |
| Gene name: | EGFR |
| Gene alias: | ERBB|ERBB1|HER1|PIG61|mENA |
| Gene description: | epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian) |
| Immunogen: | Native purified EGFR from human epidermoid carcinoma line A431. |
| Form: | Liquid |
| Recommend dilutions: | Flow Cytometry (using 1ug to stain 1 x 106 cells) The optimal working dilution should be determined by the end user. |
| Storage buffer: | In 10 mM PBS, pH 7.4 (1% BSA, 0.09% sodium azide) |
| Storage instruction: | Store at 4°C. Do not freeze. |
| Note: | This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only. |
| Conjugate tag: | Biotin |
| Product type: | Primary antibodies |
| Host species: | Mouse |
| Antigen species / target species: | Human |
| Specificity: | Recognizes the (Mr 170KDa) extracellular domain of the epidermal growth factor receptor on many cell surfaces. The EGFR mediates the initial response of cells to EGF. It has an extracellular region, which binds EGF and an intracellular region, which exhibits tyrosine kinase activity. The receptor phosphorylates a number of protein substrates in addition to mediating autophosphorylation of tyrosine residues located near its carboxyl terminus. |
| Reactivity: | Human |
| Applications: | IHC,Flow Cyt |
| Shipping condition: | Blue Ice |
| Publications: | Prevalence of aberrant expression of the epidermal growth factor receptor in human cancers.Gullick WJ. Br Med Bull. 1991 Jan;47(1):87-98. |