Brand: | Abnova |
Reference: | MAB5315 |
Product name: | CD44 monoclonal antibody, clone DF 1485 |
Product description: | Mouse monoclonal antibody raised against native CD44. |
Clone: | DF 1485 |
Isotype: | IgG1 |
Gene id: | 960 |
Gene name: | CD44 |
Gene alias: | CDW44|CSPG8|ECMR-III|HCELL|IN|LHR|MC56|MDU2|MDU3|MGC10468|MIC4|MUTCH-I|Pgp1 |
Gene description: | CD44 molecule (Indian blood group) |
Immunogen: | Native purified human CD44. |
Form: | Liquid |
Recommend dilutions: | Immunohistochemistry (1:5-1:10) The optimal working dilution should be determined by the end user. |
Storage buffer: | In tissue culture supernatant |
Storage instruction: | Store at 4°C. |
Product type: | Primary antibodies |
Host species: | Mouse |
Antigen species / target species: | Human |
Specificity: | HCAM, CD44 is a transmembrane glycoprotein which is expressed by lymphocytes and several normal epithelial cells. The CD44 molecule is involved in lymphocyte homing, T-lymphocyte actvitation, interaction with hyaluronic acid and may act as an adhesion molecule. Standard CD 44 (CD44s) is composed of the products of exons 1-5 a less favourable prognosis in gastrointestinal cancers, the loss of CD44s expression predicts unfavourable outcome in bladder cancers, squamous cell carcinomas of the skin, prostatic adenocarcinomas and neuroblastomas. In immunoblotting this antibody reacts with a glycoprotein isolated from hemopoietic cells and epithelials cells with a respective molecular weight of 29-37 and 51 kD. |
Reactivity: | Human |
Applications: | IHC-Fr,IHC-P |
Shipping condition: | Blue Ice |